Hipopituitarismo Flashcards

1
Q

Ordem de decrescente de acometimento hormonal

A

Gonadotrofinas - GH - TSH - ACTH - PRL

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2
Q

Mutações POU1F1 - deficiências

A

GH - PRL - TSH

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3
Q

Causa genética mais comum de Deficiência combinada dos hormônios hipofisários - DCHH

A

Defeitos no PROP1

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4
Q

Principal deficiência associada ao Pit1

A

GH -> depois TSH e Hipogonadismo

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5
Q

6 causas de hipopituitarismo hereditario

A
Sd de kallmann
Prader-Willi 
Mutacoes no gene PROP1
Mutações no gene POU1F1
Gene HESX1
Aplasia/hipoplasia hipofisaria
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6
Q

Mutacoes no gene HESX1 associada a qual ma formação

A

Displasia septo-optica

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7
Q

Principal causa de hipopituitarismo adquirido

A

Tu hipofisario

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8
Q

5 causas de hipopituitarismo adquirido

A
Tu hipofisario 
Hipofisite
Sd de Sheehan 
Dcas granulomatosas 
Traumatismo
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9
Q

Dose de reposicao de GH no adulto

A

0,1 a 0,4 mg/dia (0,45 a 1,2 UI/dia)

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10
Q

Apresentacoes da testo IM

A

Cipionato de testo 200mg/2ml
Esteres de testo 250 mg
Undecanoato de testo 1000 mg

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11
Q

Contraindicação ao uso de testo

A

Ca de prostata ou mama
PSA > 4
Htco > 52
ICC classes 3 e 4
Apneia obstrutiva do sono grave nao tratada
HPB com sintomas urinarios significaticos

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