Hip OA Flashcards
What occurs to the cartilage in the early and progressive changes in oa
early- localized areas of softening presenting a pebbled texture at the surface
Progression-disruption along the collagen fibre planes
What occurs in the final stages of cartilaginous changes in oa- irregular cartilage
irregular cartilage- loss of PG content, there is subsequent focal proliferation on chondrocytes leading to irrecgular cartilage
What occurs in the final stages of cartilaginous changes in oa- osteophytes, subarticular cytes
osteophytes- new bone will occur in subchndral bone and jt margins- make it look larger
Subarticular cytes- predominate where overlying cartilage is thin or absenct
What occurs in the final stages of cartilaginous changes in oa- infiltration, calcification
infiltration- synovium will thicken and hypertrophy and the capsul conracts with infiltration of lymphoid follicles
Calcification- may occur as crystals deposit in cartilgae
What scale is the gold standard for grading severity of oa
kellgren and lawrence grading scale
What % of canadian adults have arthritis
20.4
mc pop with prevalence of oa
females
african americans
What jts are mc for oa
Hip and knee
modifiable risk factors of oa
- previous jt damage
- overweight’
- heavy work
- weaknes of leg mm
- trauma
what gives you a 4x higher risk of oa
Obese women with BMI of 30-35
(obesity also a risk for bilateral oa) * most important risk factor
how does obesity contribute to oa
Adipose tissue itself is a source of inflammaory factors that are associated with alterations of cartilage homeostasis and degradation
1kg loss in weight lead to what % decrease in oa
10% decrease
What is the ratio of weight and compressive force
4:1 ratio in relation to weight and knee force
How well in knee injury associated with knee oa
knee injury was associated w a 6fold increased risk of knee oa (cruciate lig mc)
characteristics of primary oa
localized +/or generalized
small (peripheral jt) and or large (central its)
mixed and spine
erosive oa
Characteristics of secondary oa- cause
Congenital and developmental disorders, bone dysplasia post surgery (meniscectomy)
90% of oa patient also have this
1 additional chronic condition
knee oa associated with cv events and all cause mortality
Eular diagnosis guidlines for oa : imaging
- don’t need imaging to make an oa dx in pts w typical presentation
- routine imaging not nessesary
- pain film still best
what 3 signs and 3 symptoms should be used to dx oa
signs- crepitus, restricted mvmt, bony enlargemnt
symptoms- persistent knee pain, limited morning stiffness, reduced function
99% accurate w all 6
recommendations for non pharmacological therapy of oa
Strong for exercise + weight loss
-less strong for manual therapy and only in conjunction w exercise
