Hip OA

Question 1

What occurs to the cartilage in the early and progressive changes in oa

Answer 1

early- localized areas of softening presenting a pebbled texture at the surface

Progression-disruption along the collagen fibre planes

Question 2

What occurs in the final stages of cartilaginous changes in oa- irregular cartilage

Answer 2

irregular cartilage- loss of PG content, there is subsequent focal proliferation on chondrocytes leading to irrecgular cartilage

Question 3

What occurs in the final stages of cartilaginous changes in oa- osteophytes, subarticular cytes

Answer 3

osteophytes- new bone will occur in subchndral bone and jt margins- make it look larger

Subarticular cytes- predominate where overlying cartilage is thin or absenct

Question 4

What occurs in the final stages of cartilaginous changes in oa- infiltration, calcification

Answer 4

infiltration- synovium will thicken and hypertrophy and the capsul conracts with infiltration of lymphoid follicles

Calcification- may occur as crystals deposit in cartilgae

Question 5

What scale is the gold standard for grading severity of oa

Answer 5

kellgren and lawrence grading scale

Question 6

What % of canadian adults have arthritis

Answer 6

20.4

Question 7

mc pop with prevalence of oa

Answer 7

females

african americans

Question 8

What jts are mc for oa

Answer 8

Hip and knee

Question 9

modifiable risk factors of oa

Answer 9

• previous jt damage
• overweight’
• heavy work
• weaknes of leg mm
• trauma

Question 10

what gives you a 4x higher risk of oa

Answer 10

Obese women with BMI of 30-35

(obesity also a risk for bilateral oa) * most important risk factor

Question 11

how does obesity contribute to oa

Answer 11

Adipose tissue itself is a source of inflammaory factors that are associated with alterations of cartilage homeostasis and degradation

Question 12

1kg loss in weight lead to what % decrease in oa

Answer 12

10% decrease

Question 13

What is the ratio of weight and compressive force

Answer 13

4:1 ratio in relation to weight and knee force

Question 14

How well in knee injury associated with knee oa

Answer 14

knee injury was associated w a 6fold increased risk of knee oa (cruciate lig mc)

Question 15

characteristics of primary oa

Answer 15

localized +/or generalized
small (peripheral jt) and or large (central its)
mixed and spine
erosive oa

Question 16

Characteristics of secondary oa- cause

Answer 16

Congenital and developmental disorders, bone dysplasia
post surgery (meniscectomy)

Question 17

90% of oa patient also have this

Answer 17

1 additional chronic condition

knee oa associated with cv events and all cause mortality

Question 18

Eular diagnosis guidlines for oa : imaging

Answer 18

1. don’t need imaging to make an oa dx in pts w typical presentation
2. routine imaging not nessesary
3. pain film still best

Question 19

what 3 signs and 3 symptoms should be used to dx oa

Answer 19

signs- crepitus, restricted mvmt, bony enlargemnt

symptoms- persistent knee pain, limited morning stiffness, reduced function

99% accurate w all 6

Question 20

recommendations for non pharmacological therapy of oa

Answer 20

Strong for exercise + weight loss

-less strong for manual therapy and only in conjunction w exercise