Hindbrain Flashcards

0
Q

Which surface of the brainstem has the cranial nerves, pons and medulla (raphe, ventrolateral medulla) visible?

A

Ventral

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1
Q

Hindbrain and midbrain make up the?

A

brainstem

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2
Q

The dorsal surface of the brainstem contains what 6 things?

A
  • TRIGEMINAL system (processes sensory input from face)
  • Parts of vestibular system
  • Pyramidal dessucation
  • GRACILE nucleus
  • Inferior + superior colliculi
  • Cerebellar peduncles
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3
Q

Are sensory nuclei in brainstem located more laterally or medically?

A

Laterally

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4
Q

What is the role of the Edinger-Westphal nucleus?

A

Parasympathetic input to eye —> pupil constriction

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5
Q

What input does the solitary nucleus receive?

A

SENSORY afferent input from FACIAL (VII), GLOSSOPHARYNGEAL (IX), and VAGUS (X).

(Taste! Facial and glosso)

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6
Q

Which brainstem nucleus receives motor info from cranial nerves IX and X?

A

Ambiguus

Glosso. and vagus - throat muscles

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7
Q

Axons of the salivatory nucleus are parasympathetic or sympathetic?

And go via which cranial nerves?

A

Parasympathetic

Facial and GLOSSOPHARYNGEAL

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8
Q

Where do 90% of corticospinal fibres cross midline?

A

Pyramidal decussation

Caudal medulla

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9
Q

Which medullary pathology is caused by thrombosis of vertebral artery?

A

Wallenberg’s syndrome

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10
Q

What are the symptoms of Wallenberg’s syndrome?

A

1) contralateral pain/temp loss (spinothalamic)
2) ipsilatetal pain/temp loss in face (trigeminal)
3) vertigo/nystagmus (vestibular nuc)
4) ipsilatetal loss of taste (solitary nuc)
5) dysphagia (difficulty swallowing - amiguus)

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11
Q

Why is a brainstem glioma?

A

Tumour in brainstem

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12
Q

From where do reticular nuclei extend?

A

Medulla –> pons –> midbrain

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13
Q

Roles of reticular formation? (x3)

A

1) Ascending fibres control arousal - sleep, wakefulness, attention
2) Descending fibres form RETICULO-SPINAL tract - posture + postural reflexes
3) helps control HR + respiration

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14
Q

Pallidus, obscurus and Magnus are examples of what?

Where are they located?

A

Raphe nuclei

P + O - medulla
M - pons(caudal)

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15
Q

What NT do raphe nuclei contain?

A

5-HT

16
Q

Where do raphe nuclei in medulla and caudal pons project to?

What do they control?

A

Spinal cord

Modulate pain, movement and autonomic control

17
Q

Where do raphe nuclei in rostral pons and midbrain project to?

What do they control?

A

Forebrain

Mood, sleep-wake cycles

18
Q

Which raphe nuclei has a key role alongside the Periaqueductal grey in the descending pain pathway?

A

Magnus

19
Q

What is the monoamine hypothesis regarding depression?

A

Under activity of monoamines especially 5-HT

20
Q

Tricyclics, MAO inhibitors and SSRIs re treatments for depression, how do they work?

A

Tricyclics - block 5-HT reuptake

MAO inhibitors - inhibit 5-HT breakdown

SSRIs - 5-HT agonists