High Yield PPT: Emma Holliday Ramahi Flashcards
Absolute contraindication to surgery?
Diabetic Coma, DKA
What to do to try to maximize someones nutrition?
Enteral feedings
Other reasons surgeons will delay surgery?
Liver failure
Poor nutrition
When should a smoker stop smoking prior to surgery?
8 weeks!
Smoker patient: what to think of as coming out of anesthesia?
Don’t keep O2 sat at 100 % because likely chronic CO2 retainer. Hypoxia is their strongest drive for respiration.
What is Goldman’s Index?
Tells you who is at greatest risk for surgery
Most important factor in Goldman’s index (biggest predictor of peri-operative mortality)?
CHF
What should you check in patient with CHF?
Ejection fraction
(if less than 35 %, no surgery).
2nd most important indicator when predicting mortality from surgery?
MI within 6 months
Patient who comes in for pre-op evaluation and has a late systolic ejection murmur, crescendo-decrescendo?
Aortic stenosis
Meds to stop before surgery?
Aspirin NSAIDs Metformin Vit. E Warfarin
Why stop metformin?
Risk of lactic acidosis
Want INR less than?
1.5
Take what dose of insulin?
1/2 morning dose
When do you dialyze before surgery?
24 hours pre-op
Why worry if BUN > 100?
Increased risk of post-op bleeding. Uremia –> uremic toxins interact with platelets!!
Coag pannel of patient with uremic platelet dysfunction?
normal platelet count
Increased bleeding time
Good for weaning patient off of ventilator?
Pressure support
Assist-control vent setting
Set Tidal Volume and Rate…if patient takes a breath, predetermined volume still delivered
Pressure suppor vent
Patient rules rate! Boost of pressure is given if they are not able to take in entire TV on their own!
CPAP
Patient breathes on own! But + pressure given all the time in order to make sure alveoli stay open
PEEP
Keeps alveoli open in patients with ARDS or CHF…alveoli are collapsing and that’s what is causing the difficulty in facilitating gas exchange. Positive pressure only given at the END of cycle
Patient on vent…how do we want to evaluate management?
ABG
low pO2 in patient on vent
not getting enough oxygen…increase FiO2!
What does too much oxygen do?
Free radical damage…too high concentrations can worsen ARDS etc.
Patient has low PaCO2 and high pH…how can you fix it?
Decrease TV (better option because decreasing more of the air in the functional space)
or decrease rate–blow out less CO2
Anion gap equation
Na+ - (Cl- + HCO3-)
Normal anion gap
8-12
Causes of non-gap acidosis
Diarrhea**main one
Diuretic
RTAs
Why is diarrhea most common cause of non-gap acidosis?
GI tract has a lot of bicarb…if pooping a lot…getting rid of a lot of bicarb–metabolic acidosis
How to differentiate cause of metabolic alkalosis?
Check Urine Chloride
Vomiting–urine chloride will be low
High–could be genetic problem
Causes of hypervolemic hypernatremia?
CHF
Nephrotic
Cirrhotic
Next test after finding a patient with Normal volume but decreased sodium…SIADH
CXR. Paraneoplastic syndrome associated with lung cancer
Treatment of hyponatremia if patient is hypovolemic?
Normal saline
When do we use hypertonic 3 % saline?
Severly symptomatic hyponatremia (seizures, Altered mental status, or if sodium is super lowwww like less than 110)
Why don’t we use this hypertonic saline more often?
Central pontine myelinolysis
Appropriate rate of sodium correction
Between 12-24 meq/day
or 0.5-1 mEq/hour
Treatment of Hypernatremia
Replace with D5W or hypotonic fluid
Low calcium can do what to EKG
Prolonged QT interval
Symptoms of Hypokalemia
Paralysis
Ileus
ST depression
U waves
Tx of hypokalemia
Give potassium! Monitor renal function.
EKG changes of hyperkalemia?
Peaked T waves
Prolonged PR and QRS
Sine waves
Treatment of hyperkalemia
*IMPORTANT
Give:
- Calcium-gluconate-stabilize cardiac membranes
- Insulin + glucose–shift K+ into cells
What can be used besides Insulin to get K+ into cells?
B-agonist like Albuterol
Makes you poop out potassium
kayexalate
maintenance iVF of choice
D51/2NS
erythematous, not peeling
1st deg. burn
epidermis
super painful, loss of integrity of epidermis
2nd degree burn
Dark or pale, no sensation because damage goes all the way through dermis and starts to affect nerves
3rd degree burn
Patient comes in confused, headache, cherry red skin
carbon monoxide poisoning
Check carboxyhemoglobin!
Cause of clotting in old people
Cancer
New clots, edematous, high BP, foamy pee
Nephrotic syndrome
(because losing protein in urine…some of first to go-antithrombin III)–hypercoaguabule state!
Most common inherited hypercoaguablitity?
Factor V leiden
What can’t you give someone with ATIII def?
Heparin
Young woman with multiple Spontaneous abortions?
lupus anticoagulant
Post op patient with thrombocytopenia but increased clotting?
Maybe they received heparain! HIT
Treat HIT with?
Leparudin or Agatroban
isolated decrease in platelets?
ITP
Normal platelets, increased bleeding time and PTT?
vWF disease
Low platelets
coags high
schistocytes
etc…
DIC
due to gram-sepsis (LPS), carcinomatosis, OB stuff
Parkland formula
for burn patient fluid resuscitation
Adults:
Kg x %BSA x 3-4
Kids:
Kg x %BSA x 2-4
Give half in first 8 hours, the rest over the next 16 hours
Route of giving antibiotics to burn patients
TOPICAL
Can cause leukopenia
Does not penetrate eschar
Silver sulfadiazene
Penetrates eschar
hurts like hell
Mafenide
Can cause hypokalemia and hyponatremia
doesn’t penetrate eschar
Silver nitrate
Electrical burn…get what test?
EKG
Pee red but no RBC in it…
Rhabdomyolysis causing myoglobinuria
Find myoglobinuria, check?
K+ level! Can cause fatal arrhythmias
Airway if patient is unconscious?
INTUBATE
Feel subcutaneous emphysema in neck after patient stabbed
Fiberoptic bronchoscope
What do you do after you intubate patient?
listen for breath sounds
indications to take someone with hemothorax to OR
High output greater than 1.5 L during initial chest tube insertion or greater than 200 cc/hour for first 4 hours
“White out lung”
Pulmonary contusion
Tx. Control pain, wait
Flail chest
> 3 consecutive rib fractures
Moves in upon inspiration
Tx for flail chest
Nerve block (for pain control)
*Don’t give opiates–decrease resp. drive
Petechial rash in chest
Fat embolism
hypotensive, tachycardic
shock
Pulsus parodoxus
Electrical alternans
Pericardial tamponade
Confirmatory test for pericardial tamponade
FAST exam
*Then do the needle decompression
GCS subcategory breakdown of maximum points
Eyes 4
Verbal 5
Motor 6
Surgical intervention for increased ICP
ventriculostomy
Zone 3 of neck
above angle of mandible
Zone 2 of neck
angle of mandible to cricoid
Zone 1
below cricoid
W/u for zone 1
aortography and triple endoscopy
w/u zone 2
2D doppler
+/- exploratory surgery
Zone 1 w/u
Aortography
Free air under diaphragm
EX LAP
Stable patient with blunt abdominal trauma
CT
Lower rib fracture + bleeding into abdomen
Spleen or liver lac
Positive Kehr sign + viscera in thorax
diaphram rupture
(pain in left shoulder, referred pain due to phrenic nerve)–Kehr sign
Handlebar sign
Pain and bruising over pancreas
blood at urethra, high riding prostate
pelvic fracture with urethral or bladder injury
test for urethral injury
Retrograde urethrogram
Head fracture that goes to OR
Depressed skull fracture
Shoulder pain after seizure
posterior shoulder dislocation
Arm outwardly rotated, numb over deltoid (axillary nerve injury)
Ant. dislocation
Old lady FOOSH, distal radius displaced
Colle’s fracture
Hand hurts after punching wall
metacarpal neck fracture
clavicle break location
between middle and distal thirds
Fever POD1
Atelactasis
Dx of atelectasis?
Listen
CXR
Bilateral fluff in lower lobes
POD1 super high fever to 104
Nec fasc
*spread along scarpas fascia…usually due to strep and clostridium
Tx of nec fasc
OR..debridement!
With IV penicillin!!
Cause of malignant hyperthermia
Succ or halothane
Prob with ryanodine receptor gene defect
Fever POD3-5
Pneumonia
Tx of pneumonia
cover with fluoroquinolone Like Mocifloxacin in mean time in case it is strep pneumo…await culture
POD7, edema at incision site, induration, No drainage
Cellulitis
Tx. antibiotics
POD7, edema, induration, plus drainage
open wound
Re-pack it
No abx necessary
Salmon colored fluid from incision
dehiscence
treatment of dehiscence
go bak to OR
Problem is violation of the fascia.
Primary closure of fascia
IV abx
Post c-section or hysterectomy unexplained fever
Pelvic thrombophlebitis
Tx. Antibiotics, heparin
Cause of pressure ulcer
ischemia
Marjolin’s ulcer
squamous cell carcinoma in chronic ulcer
Transudative pleural effision
Low pleural glucose
Rheumatoid arthritis
Transudative effusion
High lymphoytes
tuberculosis
Bloody transudative pleural effusion
malignant or pulmonary embolus
Lights criteria
Transudative pleural effusion if
LDH < 200
LDH effusion compared to serum <0.6
Protein eff/serum <0.5
VATS
video assisted thoracic surgery
Type of abscess you don’t want to drain
Lung abscess
Tx*Antibiotics
Penicillin or Clindamycin
Lung shows a spot with air/fluid level
abscess
most common benign lung nodule…popcorn calcification
hamartoma
concentric calcifications on x-ray
old granuloma
most common type of lung cancer in non-smokers
adenocarcinoma
weird spot that adenocarcinomas like to go
Adrenal glands
Patient with kidney stones, constipation, malaise, low PTH, + central lung mass
Squamous cell carcinoma
Why low PTH in squamous cell carcinoma
Paraneoplastic syndrome
Secretion of PTH-rP
Paraneoplastic syndromes associated with small cell carcinoma
Pancoast tumor
Lambert eaton syndrome
SIADH
Peripheral lung mass, cavitating, distant mets
Large Cell carcinoma
Which lung cancers get surgery?
Non-small cell!!
Small cell is very chemo, radio sensitive.
ARDS causes
Gram - sepsis
Pancreatitis
Gastric aspiration
Criteria for ARDS criteria
Bilateral fluffy infiltrates
PaO2/FiO2 ratio <200
PCWP is < 18 (means not cardiac)
Treatment of ARDS
Vent setting on PEEP
diastolic murmur
widened pulse pressure
aortic regurgitation
Late systolic murmur with click
mitral valve prolapse
holosystolic murmur with late diastolic rumble
VSD
Tx of Zenker’s
Surgery
Bird beak on barium swallow
Achalasia
Surgery done on achalasia if medical management fails
Heller myotomy
Dysphagia worse with hot/cold liquids
Diffuse esophogeal spasm
Medical treatment of esophageal spasm and achalasia
Calcium channel blocker
Nitrates
Gastric lymphoma associated with what disease
HIV
MALT lymphoma tx
Eradicate H. Pylori
Mentriers disease
protein losing enteropathy
enlarged rugae
Mid epigastric pain better with eating
Duodenal ulcer
Triple therapy
PPI
Clarithromycin
Amoxicillin
Refractory ulcers after Triple therapy?
ZE syndrome
SMA syndrome
Happens after rapid weight loss…duodenal compressed between abdominal aorta and SMA
How does one get gastric varices from pancreatitis?
Pancreatitis can cause splenic vein thrombosis…which leads to gastric varices.
Courvoisier’s sign
large nontender GB
Itching and jaundice
*Adenocarcinoma of pancreas
Trousseau’s sign
Migratory thrombophlebitis
Pancreatic cancer dx
Endoscopic US and FNA biopsy
When is pancreatic tumor deemed resectable
No mets outside abdomen
no extension into SMA, portal vein, liver, etc.
Whipple’s triad (insulinoma)
Sxs (sweat, tremors, hunger, seizures)
Blood glucose <45
Sx resolve when glucose administered
Glucagonoma sx
hyperglycemia
diarrhea
weight loss
characteristic rash of glucagonoma
necrolytic migratory erythema
VIPoma sx
watery diarrhea flushing hypokalemia dehydration flushing
Pentad: RUQ pain Fever Jaundice Decrease BP Altered mental status
Ascending cholangitis
liver bacterial abscess bugs
E. Coli
Bacteroides
Enterococcus
Treatment for entamoeba histolytica
Metronidazole
RUQ pain with large liver cysts
enchinococcus (from dog feces)
Skin test for enchinococcus
+Casoni test
Tx for echinococcus
SURGERY + Albendazole
Remove entire cyst, rupture = anaphylaxis
what happens to carcinoid tumor to get syndrome?
Mets!
If was just in GI tract, serotonin would be denatured before it got out
1 spot for carcinoid tumor
appendix
vitamin ppl with carcinoid syndrome def. in?
Niacin!
Serotonin and niacin both made from tryptophan! All is being used to make serotonin
diarrhea, dementia, dermatitis
Transmural inflammation
Crohns
Granulomas
Crohns
Smokers have low risk
UC
Smokers have high risk
Crohns
Higher risk for colon cancer: Crohns or UC?
UC
Associated with p-ANCA
UC! and PSC!
1 cause of death post AAA repair
MI
Post AAA repair 1-2 years later have GI bleeding
Aortoenteric fistula
W/u for mesenteric ischemia
angiography
Best test for PAD
ABI
Blood thinner regimen for DVT
Treat with heparin
Overlap heparin for 5 days with Warfarin
Continue warfarin 3-6 months
Hashimoto’s predisposes to….
Thyroid lymphoma
Breast cancer that is more often bilateral
LCIS
Orange peel skin on breast
Inflammatory BC
Eczema of nipple
Paget’s Disease of breast
Precursor to squamous cell carcinoma of skin
actinic keratosis
number one prognostic indicator of melanoma
Depth
Dx of sarcoma
BIOPSY
not FNA
Where does sarcoma like to spread to first? How?
LUNGS
Hematogenously
Osteosarcoma
Proximal femur, distal tibia
Codman’s triangle and sunray appearance on x-ray
Cause of hyperacute rejection
preformed antibodies
cause of acute rejection
T cell reaction
Treatment of acute rejection
Steroid bolus
+ Antilymphocyte agent (OKT3)
What do you do for chronic rejection
re-transplantation