High Yield - OMFS Flashcards
What test is needed for a patient on Warfarin/Coumadin?
INR (prothrombin time)
Should be under 3
What is the mode of action for Warfarin/Coumadin?
Decrease K+. Needed to synthesize factors II, VII, IX, X
T/F: The effects of Warfarin are seen immediately, and they go away abruptly upon stopping the med.
False
A few days for effect to occur. Can last up to 5 days after stopping
What is the mode of action of heparin?
Binds to and activates antithrombin III. Leads to inactivation of thrombin, factor Xa. This interrupts fibrinogen -> fibrin.
What is a normal INR?
1.
2-3 is desirable in Coumadin patients.
Higher equals more bleeding
What can reverse Coumadin?
Vitamin K supplement
T/F: An INR should be ordered for a severe alcoholic.
True
Which test will asses platelet function?
Bleeding time.
Aspirin affects this.
What will be the effect of inhibiting prostaglandins?
Increase gastric acid. Decrease gastric mucous
What is a normal hematocrit (RBC) level?
Men = 45% Women = 40%
T/F: The INR/PT asses the extrinsic clotting pathway.
True
T/F: PTT assesses the intrinsic clotting pathway.
True
Pts with hemophilia A are missing what clotting factor?
Factor VIII
T/F: Glucocorticoids are indicated for diabetic patients.
False
Why would Sulfonylurea not be effective in Type I diabetes pts?
Sulfonylurea stimulates beta cells in pancreas to release more insulin.
Type I diabetics lack beta cells
What type of channels do Sulfonylurea drugs bind to?
ATP-dependent K+ channels
What is the MOA of metformin?
Decreases glucose production in liver
Which molecule (insulin/glucagon) would cause a decrease in glycogenolysis in the liver?
Insulin.
Blood glucose high -> insulin released -> increase in glycogenesis and lipogenesis; decrease in glycogenolysis and lipogenolysis
T/F: There is more bacteria found in gingiva of diabetic patients.
False
What is the HbA1c for controlled diabetes?
Normal: 4-6
Increased: 7-8
Uncontrolled: >8
T/F: Epinephrine is contraindicated in hyperthyroidism patients.
True
What is given to an unconscious patient in hypoglycemic shock?
50% dextrose IV
What are common symptoms of CHF?
Orthopnea (SOB when laying flat) and dyspnea (SOB when exercising)
What is the most common reason for heart problems in kids?
Respiratory failure
What is Digitalis and how does in work?
Cardiac glycoside. Increase CO (treat CHF). Blocks Na/K/ATPase allowing more Ca influx
What med should be avoided in patient on Ginsing?
Aspirin
What are some side effects of nitroglycerin?
Orthostatic hypotension and headaches
T/F: Patients should take nitroglycerin during a TIA.
False
Angina
_____ patients have trouble inhaling, while _____ patients have trouble exhaling.
Asthma; COPD
What can occur after air is blown into the sulcus?
Soft tissue emphysema
What does a crowing sound or Stridor sound indicate?
Laryngospasm. Blockage of upper resp tract
Which pain relievers are contraindicated in asthmatics?
NSAIDs
T/F: Patient starts wheezing, it is important to give O2 as quickly as possible.
False
No O2 for asthma patients
T/F: Pregnant patients should lay on left side.
True
Takes pressure off of Vena cava preventing syncope
What is the trendelenburg position?
Supine with feet slightly elevated. Used for syncope
T/F: Syncope can be treated with 100% O2.
True
Except hyperventilation syndrome
What is the most common dental complication in chair?
Syncope
What medication should be given to a patient experiencing grand mal seizure?
Dilantin (phenytoin)
What drug is indicated for status epilepticus (long seizure)?
Diazepam (valium)
Pregnancy, myasthenia gravis, and acute narrow glaucoma are all contraindications for _______.
Diazepam
________ can cause seizures.
Hyponatremia
_______ has a very low risk of resp depression in regards to benzos.
diazepam
Serious drug interaction between MAO inhibitor and which opioid?
Meperidine
What are some symptoms of opioid overdose?
Hypothermia, Hypotension, miosis, respiratory depression
What is the role of an antagonist?
High affinity, no intrinsic activity
Which opiate is given as a transdermal patch?
Fentanyl
What is the reversal agent for opioids?
Naloxone
What drug is used for recovering opioid addicts?
Methadone
T/F: Mu receptors are found in the medulla.
True
What pain relievers can you give a patient with a codeine allergy?
NSAIDs, Naproxen, Meperidine, tramadol,
Why do 2nd generation antihistamines not cause drowsiness?
They do not cross the BBB.
Most end in -tidine
T/F: Benedryl (diphenhydramine) causes xerostomia.
True
Anticholinergic effect
T/F: H1 blockers are used for gastric ulcers.
False
H1: nasal
H2: gastric
T/F: Tylenol can cause liver toxicity.
True
T/F: Plavix and aspirin inhibit platelet aggregation.
True
How long after stopping will aspirins anti-coag effects continue?
7 days
T/F: Saw Palmetto enhances anti-coagulants.
True
T/F: The ceiling analgesia of Ibuprofen is reached at 400mg.
True
600mg best for anti-inflammation
T/F: Celebrex is a COX2 inhibitor that does not cause coagulation.
True
Which pain reliever is preferred in patients with kidney problems? Liver problems?
Acetaminophen is best for kidney failure.
NSAIDs better for liver failure.
Best pain med for pregnant patient?
Tylenol
T/F: Codeine is indicated in a breastfeeding mother.
False
Drugs are scheduled based on potential for _____.
abuse
Morphine, cocaine, methadone, hydrocodone, and fentanyl are all schedule ___ drugs.
Schedule 2
Codeine products with Tylenol or aspirin are schedule __ drugs.
Schedule 3
Most benzodiazepines are schedule ___ drugs.
Schedule 4
T/F: Vicodin is a schedule 2 narcotic.
False
Schedule 3
Since it has less than 15mg hydrocodone
What NSAID lasts for 8 hrs?
Naproxen
What is the most difficult impaction to remove?
Mandibular distoangular
When is distraction osteogenesis preferred over normal osteotomy?
When a large advancement is needed
T/F: Arthrocentesis is considered a surgical treatment.
False
T/F: Local anesthetics have the direct effect of vasoconstriction.
False
Epinephrine causes vasoconstriction. LA itself causes dilation
T/F: Lidocaine can be packaged with and without epinephrine.
True
What is the pKa of lidocaine?
7.9
What is the proper position for LA injection?
Supine. Helps prevent syncope
What is considered slow delivery of LA?
1 carp over 1 minute
What is the proper depth of insertion for PSA?
16mm. Half length of long needle.
What is the adequate amount of anesthesia for an ASA block?
1/2 carp
T/F: Lower pKA results in faster onset.
True
What are the most important factors for duration of action for LA?
Lipid solubility and protein binding. Bupivicaine is longest acting LA
T/F: Articaine has a relatively short half-life.
True
What is the first step in taking a biopsy on a soft tissue lesion deep to mucosa?
Aspirational biopsy