High Yield - OMFS Flashcards
What test is needed for a patient on Warfarin/Coumadin?
INR (prothrombin time)
Should be under 3
What is the mode of action for Warfarin/Coumadin?
Decrease K+. Needed to synthesize factors II, VII, IX, X
T/F: The effects of Warfarin are seen immediately, and they go away abruptly upon stopping the med.
False
A few days for effect to occur. Can last up to 5 days after stopping
What is the mode of action of heparin?
Binds to and activates antithrombin III. Leads to inactivation of thrombin, factor Xa. This interrupts fibrinogen -> fibrin.
What is a normal INR?
1.
2-3 is desirable in Coumadin patients.
Higher equals more bleeding
What can reverse Coumadin?
Vitamin K supplement
T/F: An INR should be ordered for a severe alcoholic.
True
Which test will asses platelet function?
Bleeding time.
Aspirin affects this.
What will be the effect of inhibiting prostaglandins?
Increase gastric acid. Decrease gastric mucous
What is a normal hematocrit (RBC) level?
Men = 45% Women = 40%
T/F: The INR/PT asses the extrinsic clotting pathway.
True
T/F: PTT assesses the intrinsic clotting pathway.
True
Pts with hemophilia A are missing what clotting factor?
Factor VIII
T/F: Glucocorticoids are indicated for diabetic patients.
False
Why would Sulfonylurea not be effective in Type I diabetes pts?
Sulfonylurea stimulates beta cells in pancreas to release more insulin.
Type I diabetics lack beta cells
What type of channels do Sulfonylurea drugs bind to?
ATP-dependent K+ channels
What is the MOA of metformin?
Decreases glucose production in liver
Which molecule (insulin/glucagon) would cause a decrease in glycogenolysis in the liver?
Insulin.
Blood glucose high -> insulin released -> increase in glycogenesis and lipogenesis; decrease in glycogenolysis and lipogenolysis
T/F: There is more bacteria found in gingiva of diabetic patients.
False
What is the HbA1c for controlled diabetes?
Normal: 4-6
Increased: 7-8
Uncontrolled: >8
T/F: Epinephrine is contraindicated in hyperthyroidism patients.
True
What is given to an unconscious patient in hypoglycemic shock?
50% dextrose IV
What are common symptoms of CHF?
Orthopnea (SOB when laying flat) and dyspnea (SOB when exercising)
What is the most common reason for heart problems in kids?
Respiratory failure
What is Digitalis and how does in work?
Cardiac glycoside. Increase CO (treat CHF). Blocks Na/K/ATPase allowing more Ca influx
What med should be avoided in patient on Ginsing?
Aspirin
What are some side effects of nitroglycerin?
Orthostatic hypotension and headaches
T/F: Patients should take nitroglycerin during a TIA.
False
Angina
_____ patients have trouble inhaling, while _____ patients have trouble exhaling.
Asthma; COPD
What can occur after air is blown into the sulcus?
Soft tissue emphysema
What does a crowing sound or Stridor sound indicate?
Laryngospasm. Blockage of upper resp tract
Which pain relievers are contraindicated in asthmatics?
NSAIDs