high yield abx

Question 1

Pen G formulation

Answer 1

IV & IM

Question 2

bacteria covered by OG penicillins

Answer 2

GP

Question 3

indications for OG penicillin

Answer 3

1. Syphilis
2. Strep Pharyngitis
3. Dental Infection
4. Rheumatic Fever

Question 4

the penicillinase-resistant/anti-staphylococcal penicillin

Answer 4

dicloxacillin

Question 5

bacteria covered by penicillinase-resistant penicillin

Answer 5

MSSA-GP
bacteria, endocarditis, cellulitis– if its from MSSA you use these

Question 6

the two aminopenicillins

Answer 6

amoxicillin (PO)
ampicillin (parental)

Question 7

high yield indications for aminopenicillins

Answer 7

acute otitis media
strep pharyngitis
listeria
UTIs in pregnancy, Lyme in pregnancy or young, H. pylori

Question 8

name the aminopenicillin-beta-lactamase inhibitors

Answer 8

amoxicillin-clauvanate (augmentin)

Question 9

bacteria covered by augmentin

Answer 9

ANAEROBES
GP, GN

Question 10

what is first line for acute sinusitis

Answer 10

augmentin

Question 11

high yield indicators for augmentin

Answer 11

acute sinusitis
animal/human bites
aspiration pneumoniae

Question 12

what is preferred for lyme disease?

Answer 12

doxycycline– except if they are pregnant or young

Question 13

name your antipseudomonal penicillin

Answer 13

Piperacillin-tazobactam (zosyn)

Question 14

bacteria covered by piperacillin-tazobactam

Answer 14

PSEUDOMONAS
anaerobes
GP,GN

Question 15

ADR for penicillin class

Answer 15

hypersensitivity & hematologic rxns
GI SE w/ ampicillin, amoxicillin, augmentin)

Question 16

name the two 1st gen cephalosporin

Answer 16

CEPHALEXIN
cefazolin

Question 17

High yield indications for 1st gen ceph

Answer 17

1. skin infection (MSSA)– cephalexin
2. surgical prophylaxis– cefazolin

Question 18

the two broad spectrum cephalosporin

Answer 18

3rd & 4th gen

Question 19

2nd gen cephalosporins

Answer 19

2 FURry FOX on the PROwl
cefuroxime
cefoxitin
cefprozil

Question 20

which 2nd gen ceph covers anaerobes

Answer 20

cefoxitin

Question 21

high yield indications for 2nd gen cephalosporins

Answer 21

intra-abdominal
pelvic infections

Question 22

3rd gen cephalosporins

Answer 22

TRI- TAX-DIME
CEFTRIAXONE
CEFTAZIDIME
cefdinir
cefpodoxime

Question 23

in which generation does S. aureus coverage drop off

Answer 23

3rd gen cephalosporin

Question 24

bacteria covered by 3rd gen ceph

Answer 24

ceftazidime– pseudomonas
great GN coverage

Question 25

high yield indications for 3rd gen cepha

Answer 25

STIs, ear infections
Gonococcal infections
Meningitis– Ceftriaxone
Community-acquired pneumonia

Question 26

what bacteria is covered by cefepime

Answer 26

Pseudomonas
best GN coverage

Question 27

name the one 5th gen cephalosporin

Answer 27

ceftaroline

Question 28

specific use for ceftaroline

Answer 28

MRSA

Question 29

name the one monobactam

Answer 29

aztreonam

Question 30

what kind of bacteria is covered by monobactam

Answer 30

aerobic GN including pseudomonas

Question 31

which class is the go-to if they have hx of anaphylaxis to PCN or beta-lactams

Answer 31

monobactam like aztreonam

Question 32

two benefits of using aztreonam

Answer 32

no cross rxn w/ other b-lactam abx
no renal toxicity

Question 33

name 3 carbapenems

Answer 33

Meropenem
Imipenem– leads to necrosis of proximal renal tubules
Ertapenem

Question 34

what bacteria is covered by carbapenems

Answer 34

all except ertapenem does NOT cover pseudomonas

Question 35

ADR of carbapenem

Answer 35

lower seizure threshold
CNS toxicity

Question 36

name 3 aminoglycosides

Answer 36

gentamicin
tobramycin
amikacin

Question 37

type of bacteria covered by aminoglycosides

Answer 37

gram negative– pseudomonas