High Yield Flashcards

1
Q

G s-alpha

A

Adenylyl Cyclase
cAMP (Increased)
Beta-adrenergic (epinephrine) receptor, glucagon, serotonin, vasopressin

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2
Q

G i-alpha

A

Adenyl Cyclase & K+ Channel
cAMP (decreased) & change in membrane potential
alpha-adrenergic receptor

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3
Q

G olfa-alpha

A

Adenyl Cyclase
cAMP (increased)
odorant receptors in the nose

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4
Q

G q-alpha

A

Phospholipase C
IP3, DAG (increased)
*don’t need to know receptor

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5
Q

G o-alpha

A

Phospholipase C
IP3, DAG (increased)
acetylcholine recptor in endothelial cells

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6
Q

G t-alpha

A

cGMP phosphodiesterase
cGMP (decreased)
rhodopsin (light receptor) in rod cells

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7
Q

Adrenaline (Epinephrine)

A

Adrenal Gland
Derivative of tyrosine
Increases BP, HR, metabolism
GPCR

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8
Q

Cortisol (Corticosterone)

A

Adrenal Gland
Steroid
Affects metabolism of proteins, inflammation
Intracellular receptor (TF)

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9
Q

Estradiol

A
Ovary
Steroid
Induces and maintains female secondary sex
Intracellular receptor (TF)
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10
Q

Glucagon

A

alpha cells of pancreas
Protein
glucose regulation
GPCR

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11
Q

Growth Hormone

A

Pituitary gland
Protein
growth and muscle mass
cytokine/tyrosine kinase-associated receptor

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12
Q

Insulin

A

beta cells of pancreas
protein
glucose regulation
RTK

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13
Q

Testosterone

A

Testis
steroid
induces and maintains male secondary sex characteristics
intracellular receptor (TF)

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14
Q

Thyroid hormone (T3, thyroxine)

A

Thyroid gland
tyrosine derivative
stimulates metabolism
intracellular receptor (TF)

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15
Q

Vitamin D

A

Kidney
Steroid
Bone metabolism
Intracellular receptor (TF)

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16
Q

Epidermal Growth Factor

A

Various cells
Protein
Stimulates epidermal and others to divide
RTK

17
Q

Platelet-Derived growth factor

A

Various cells, including platelets
Protein
Stimulates many cells to proliferate
RTK

18
Q

Nerve Growth Factor

A

Various innervated tissues
Protein
Promotes survival of neurons
RTK

19
Q

Transforming Growth Factor-B (TGF-B)

A

Many cell types
Protein
Inhibits cell proliferation, stimulates ECM
Serine/threonine receptor kinase

20
Q

Nitric Oxide

A

Nerve, endothelial, BV, testis
dissolved gas
smooth muscle relaxation, nerve cell activity
None

21
Q

Acetylcholine

A

Nerve terminals
choline derivative
excitatory
GPCR

22
Q

gamma aminobutyric acid (GABA)

A

Nerve terminals
Derivative of glutamic acid
inhibitory
GPCR

23
Q

Which Apo activates LPL?

A

ApoC-II

24
Q

Which Apo allows for uptake of chylomicron remnants?

A

ApoE

25
Q

Which Apo allows LDL to be taken up by the LDL receptor?

A

ApoB-100

26
Q

Which Apo activates LCAT?

A

ApoA-I