HIGH YIELD Flashcards
1
Q
symptoms of myopathy?
A
weakness as the main
other less common symptoms: myalgia cramps fatigue dysphagia dyspnea
2
Q
diagnostic studies?
A
serum creatine kinase muscle biopsy determined by EMG and clinical exam and can show specific findings like: -polymyositis -mitochondrial myopathy -congenital myopathies
3
Q
what are the x-linked recessive muscular dystrophies?
A
dystrophin deficient
- duchenne, deleted
- becker, reduced
emery-dreifuss (rare)
4
Q
what are the autosomal dominant muscular dystrophies?
A
facioscapulohumeral
- scapular winging
- facial weakness and foot drop
- caused by deletion of chromosome 4q35
myotonic I/II
- worse distally
- increased muscle tone
- systemic involvement, hypogonadism and cataracts
5
Q
what are the autosomal recessive muscular dystrophies?
A
limb girdle
distal
6
Q
t/f, CMT is not a musclar dystrophy?
A
T
7
Q
polymyositis/dermatomyositis is what type of inflammation?
onset?
A
perivascular
usually acute to subacute, days to weeks
8
Q
typical patient with a myopathy presents with?
A
inclusion body myositis
- greater than 50 yrs age
- distribution of weakness
- quadriceps weaker than hip flexors
- long fingers and wrist flexors
- unilateral
