HIGH YIELD Flashcards
clinical classification of peripheral neuropathies?
mononeuropathies
mononeuropathy multiplex
polyneuropathies
○Entrapment/compression
○ Trauma
○ Infection
what classification of peripheral neuropathies is this?
Mononeuropathies
what classification of peripheral neuropathies is this?
○ Entrapment/compression
○ Diabetes
○ Vasculitis
Mononeuropathy multiplex
what classification of peripheral neuropathies is this?
○ Sensorimotor ○ Sensory, large fiber ○ Sensory, small fiber ○ Sensory, mixed fiber ○ Autonomic ○ Motor
Polyneuropathies
EDX in polyneuropathy equates to what degeneration?
axonal degeneration
this is an acquired syndrome and a common demylineating polyneuropathy?
guillan barre syndrome
what is the criteria of guillan barre syndrome?
necessary criteria?
supportive criteria?
necessary:
1. Acute/subacute paralysis (Usually ascending, can be descending; can lead to respiratory failure)
- Areflexia or hyporeflexia (particularly in the affected limbs)
supportive:
- Subjective > objective sensory manifestations
- No sphincteric disturbance
- Frequent history of preceeding viral syndrome
- High CSF protein after the first week
- EMG evidence of demyelination (conduction slowing and/or block)
Slowly progressive Sensorimotor demyelinating polyneuropathy Pes cavus/hammer toes Palpable greater auricular nerve Positive family history
what is this?
Charcot-Marie-Tooth disease type I (CMT1)
common chronic axonal poly neuropathies:
metabolic -diabetes mellitus -chronic renal failure -hypothyroidism -not hypokalemia toxic -alcohol
painful axonal sensorimotor polyneuropathy with mees lines?
chronic arsenic or thallium poisoning
symptomatic tx is indicated for?
pain control
treat DM peripheral neuropathy with?
gabapentin, gabitril, carbamezapine
*anticonvulsants
treat chronic axonal polyneuropathy with?
duloxetine, amtripiline, nortryptiline
antidepressants (TCAs)
local agents used for peripheral neuropathy?
capsaicin
lidocaine
