Hiearchy of muscle structure Flashcards

1
Q

what is the hiearchy of muscle from smallest to largest?

A
  1. myofilament
    2.myofibril
    3.Muscle cell/fiber
    4.fascicle
    5.whole muscle
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2
Q

What is a myofilament?

A

an individual protein that provide structure to skeletal muscle and help with CONTRACTION and regulating contraction

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3
Q

actin is a ____ fiament

A

thin

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4
Q

what is actin?

A

a contractile protein that binds with myosin to generate force

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5
Q

what is tropomyosin?

A

a regulatary protein that wraps around actin

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5
Q

What is troponin?

A

a regulatory protein that binds to actin and serves as a Ca+ receptor and pushes tropomyosin OFF active binding sites changing shape

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6
Q

What are the three types of troponin?

A
  1. troponin T (TnT)
  2. Troponin I (TnI)
    3.Troponin C (tnC)
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6
Q

What does troponin T (TnT) do?

A

binds to tropomyosin to lock actin and tropomyosin together

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7
Q

what does troponin I (TnI) do?

A

binds to actin to lock actin and tropomyosin together

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8
Q

what does troponin C do?

A

binds with Ca+ and moves tropomyosin OFF active binding sites which changes shape

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9
Q

What are the thin filaments?

A

Actin
tropomyosin
troponin

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10
Q

what are the thick filaments?

A

myosin
myofibril
muscle cell/fiber

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11
Q

What is myosin?

A

-main component of thick filaments
-CONTRACTILE protein thats binds with actin to generate force

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12
Q

For 1 myosin there are ____ actin

A

explanation: for evrery ONE thick filament, there are SIX thick filaments

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13
Q

what do structural filaments do?

A

help with allignment of thick and thin fillaments

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14
Q

what is a myofibril?

A

a bundle of myofilaments

15
Q

The ____ is the functional unit of a myofibril

A

sacromere

16
Q

Part of a sacromere:
Z-disk/line

A

the edge

17
Q

Part of a sacromere:
M-line

A

the center

18
Q

part of a sacromere:
I band

A

JUST actin

19
Q

part of a sacromere:
H-zone

A

just Myosin

20
Q

part of a sacromere:
A band

A

myosin and actin overlap

21
Q

which band gets smaller when a muscle contracts?

A

I band gets smaller at contraction

22
Q

which band gets larger when muscle contracts?

A

A band get larger

23
Q

Part of a mucle cell:
Sarcolemma

A

the muscle cell plasma membrane

24
Q

Part of a mucle cell:
Satellite cell

A

other type of muscle cell that regulates growth and mucular adaptations

25
Q

Part of a mucle cell:
transverse tubules

A

highways for APs that run inward from sarcloemma to myofibrils

26
Q

Part of a mucle cell:
Sarcoplasmic reticulum (SR)

A

network of tube that surrond myofibrils and are the STOREHOUSE for calcium

27
Q

Part of a mucle cell:
Terminal cisternae

A

enlarged portions of the SR for Calcium (Ca+) strorage

28
Q

Part of a mucle cell:
Mitochondria

A

factories that produce ATP using O2

29
Q

Part of a mucle cell:
Nuclei

A

control center for muscle cell/fiber

30
Q

What is a fascicle made up of?

A

a bundle of mucle cells/fibers

31
Q

what is a whole muscle made up of?

A

a bundle of fascicles

32
Q

How does tropomyosin act in a relaxed muscle?

A

tropomyosin blocks active binding sites on actin which prevents myosin from binding with actin

33
Q

How does tropmyosin act in presence of Calcium?

A

it gets pushed off active binding sites so myosin and actin can bind which then generates muscle force

34
Q

collagen, elastin, titin, nebulin, myomesin, and dystrophin are all…

A

structural filaments

35
Q

Where is the mitochondria is a muscle cell?

A

in the muscle sarcoplasm