Hiearchy of muscle structure Flashcards

(37 cards)

1
Q

what is the hiearchy of muscle from smallest to largest?

A
  1. myofilament
    2.myofibril
    3.Muscle cell/fiber
    4.fascicle
    5.whole muscle
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2
Q

What is a myofilament?

A

an individual protein that provide structure to skeletal muscle and help with CONTRACTION and regulating contraction

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3
Q

actin is a ____ fiament

A

thin

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4
Q

what is actin?

A

a contractile protein that binds with myosin to generate force

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5
Q

what is tropomyosin?

A

a regulatary protein that wraps around actin

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5
Q

What is troponin?

A

a regulatory protein that binds to actin and serves as a Ca+ receptor and pushes tropomyosin OFF active binding sites changing shape

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6
Q

What are the three types of troponin?

A
  1. troponin T (TnT)
  2. Troponin I (TnI)
    3.Troponin C (tnC)
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6
Q

What does troponin T (TnT) do?

A

binds to tropomyosin to lock actin and tropomyosin together

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7
Q

what does troponin I (TnI) do?

A

binds to actin to lock actin and tropomyosin together

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8
Q

what does troponin C do?

A

binds with Ca+ and moves tropomyosin OFF active binding sites which changes shape

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9
Q

What are the thin filaments?

A

Actin
tropomyosin
troponin

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10
Q

what are the thick filaments?

A

myosin
myofibril
muscle cell/fiber

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11
Q

What is myosin?

A

-main component of thick filaments
-CONTRACTILE protein thats binds with actin to generate force

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12
Q

For 1 myosin there are ____ actin

A

explanation: for evrery ONE thick filament, there are SIX thick filaments

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13
Q

what do structural filaments do?

A

help with allignment of thick and thin fillaments

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14
Q

what is a myofibril?

A

a bundle of myofilaments

15
Q

The ____ is the functional unit of a myofibril

16
Q

Part of a sacromere:
Z-disk/line

17
Q

Part of a sacromere:
M-line

18
Q

part of a sacromere:
I band

19
Q

part of a sacromere:
H-zone

20
Q

part of a sacromere:
A band

A

myosin and actin overlap

21
Q

which band gets smaller when a muscle contracts?

A

I band gets smaller at contraction

22
Q

which band gets larger when muscle contracts?

A

A band get larger

23
Part of a mucle cell: Sarcolemma
the muscle cell plasma membrane
24
Part of a mucle cell: Satellite cell
other type of muscle cell that regulates growth and mucular adaptations
25
Part of a mucle cell: transverse tubules
highways for APs that run inward from sarcloemma to myofibrils
26
Part of a mucle cell: Sarcoplasmic reticulum (SR)
network of tube that surrond myofibrils and are the STOREHOUSE for calcium
27
Part of a mucle cell: Terminal cisternae
enlarged portions of the SR for Calcium (Ca+) strorage
28
Part of a mucle cell: Mitochondria
factories that produce ATP using O2
29
Part of a mucle cell: Nuclei
control center for muscle cell/fiber
30
What is a fascicle made up of?
a bundle of mucle cells/fibers
31
what is a whole muscle made up of?
a bundle of fascicles
32
How does tropomyosin act in a relaxed muscle?
tropomyosin blocks active binding sites on actin which prevents myosin from binding with actin
33
How does tropmyosin act in presence of Calcium?
it gets pushed off active binding sites so myosin and actin can bind which then generates muscle force
34
collagen, elastin, titin, nebulin, myomesin, and dystrophin are all...
structural filaments
35
Where is the mitochondria is a muscle cell?
in the muscle sarcoplasm