Hf

Question 1

Acute heart failure mgt

Answer 1

Furosemide
Dopa and dobutamine
Nitroprusside, ntg, nesiritide
Levosimendan
Conivaptan
Tolvaptan

Question 2

V1 and V2 receptor - txt : euvolemic hyponat

Answer 2

Conivaptan

Question 3

V2 antagonist - txt: acute heart failure and hyponat

Answer 3

Tolvaptan

Question 4

Beta 2 adrenoceptor blocker
Can be given to diastolic and systolic failure

Answer 4

Nevibolol

Question 5

Given only to patient when diuretics and ace in have failed to control SYMPTOMS OF CHRONIC HF

Answer 5

Digoxin

Question 6

A VENODILATORS
Use in patient with increasing filling pressure and dsypnea

Answer 6

Nitrates

Question 7

Give to the pt with left ventricular dysfunction but no edema
Combined with diuretics as FIRST LINE THERAPY FOR HF

Answer 7

Ace in and ARBS

Question 8

Used in pt with moderate to severe hf

Answer 8

Spironolactone and eplerenone

Question 9

No limitations on ordinary physical act and symptoms occur only with greater than ordinary exercise

Answer 9

Class 1

Question 10

No symp at rest , but fatigue less than ordinary Physical act

Answer 10

Class 3

Question 11

Slight limitations of ordinary act, results to fatigue and palpitations with ordinary activity

Answer 11

Class 2

Question 12

Assoc symptoms even with at rest

Answer 12

Class 4

Question 13

Arteriolar dilators
Txt - pt with fatigue due to dec left ventricular output

Answer 13

Hydralazine

Question 14

Sglt2 Inhi
Reduce hospitalization

Answer 14

Empagliflozin

Question 15

Sglt2 Inhi
Reduce hospitalization

Answer 15

Empagliflozin

Question 16

Glp1 agonist

Answer 16

Liraflutide

Question 17

Glp1 agonist

Answer 17

Liraflutide

Question 18

Neuregulin ggf2 protein
Benefits with HF AND DIABETES

Answer 18

Cimaglermin

Question 19

Beta ADRENOCEPTOR BLOCKER

Answer 19

M C B N

METOPROLOL
CARVEDILOL
BISOPROLOL BUCINDOLOL
NEBIVOLOL

Question 20

ANP AND URODILANTIN

Answer 20

Carperitide and ularitide

Bosentan and tezosentan

Question 21

Orally active competitive inhibitors of endothelin

Answer 21

Bosentan and tezosentan

Question 22

Approved for PULMUNARY HTN

SE: teratogenic and hepatotoxic

Answer 22

BOSENTAN

Question 23

Bnp

Answer 23

Nesiritide
Sacubitril

Question 24

Useful diagnostic or prognostic test

Answer 24

BNP

Question 25

Synthetic form of Bnp Use in acute cf

Answer 25

Nesiritide

Question 26

Moa: increase cgmp in sm and reduce venous and arteriolar tone With SE : excessive hypotension

Answer 26

Nesiritide

Question 27

Prodrug - metab to ACTIVE NEPRILYSIN INHI plus an ARB ( valsartan ) Approved for HF-rEF

Answer 27

Sacubitril

Question 28

Vasodilators

Answer 28

H I HYDRALAZINE ISDN

Question 29

Provide reduction in preload ( venodilation) and reduction in afterload (arteiolar dilation)

Answer 29

Vasodilator

Question 30

Long term vasodilation, reduce damaging remodeling of the heart

Answer 30

HYDRALAZINE AND ISDN

Question 31

Venous dilator, REDUCE PRELOAD Txt- pt with high FILLING PRESSURE with dyspnea — pulmonary congestion

Answer 31

ISDN

Question 32

Arteriolar dilator, reduce afterload , inc forward CO TXT- pt with low lef ventricular output complaining fatigue

Answer 32

Hydralazine

Question 33

Arbs

Answer 33

C A L CANDESARTAN ALISKERIN LOSARTAN

Question 34

Renin inh approved for hypertension

Answer 34

Aliskiren

Question 35

First line in mgt of pt with LEFT VENTRICULAR DYSFUNCTION Without edema

Answer 35

Ace in

Question 36

Fist line txt - CHRONIC HF by reduce preload and afterload in ASYMPTOMATIC PATIENT With SE: incessant cough

Answer 36

Ace in

Question 37

It slows the progression of ventricular dilation thus slow the downward spiral of the heart

Answer 37

Enalapril

Question 38

Reduce peripheral resistance —- reduce afterload ** reduce salt and water retention ( reducing aldosterone secretion ) —— reduce preload

Answer 38

Captopril

Question 39

Drugs without POSITIVE INOtropic used in HF

Answer 39

Diuretics Ace in Arbs Vasodilators Bnp ANP Beta adrenoceptor blocker

Question 40

Steroid deriv Inhibiting Na/ K ATPase but in addition it FACILITATES SEQUESTRATION OF CA BY THE SR

Answer 40

Istaroxime

Question 41

Sensitize the tropinin sys to calcium Inhibit PDE, cause vasodilation

Answer 41

Levosimendan

Question 42

Iv agents - activates cardiac myosin and prolong systole without increasing o2 consumption of the ❤️

Answer 42

Omecative mecarbil

Question 43

Beta adrenoceptor agonist

Answer 43

DD

Question 44

B 1 selective ago ( inc camp ) Increase in CO AND DECREASE in VFP

Answer 44

Dobutamine

Question 45

CI: pheochromocytoma and tachyarrythmia

Answer 45

DOBUTAMINE

Question 46

Stimulation of peripheral posjuctional D1 and prejunctional D2 receptors Use in hf if need mag increase ng BP

Answer 46

Dopamine

Question 47

PDE INH

Answer 47

Bipyridines ** Milrinone Inamrinone Amrinone

Question 48

Inhibits PDE 3 and less like to cause bone marrow and liver toxicity

Answer 48

Milrinone

Question 49

Incre inward calcium influx in ❤️ during AP

Answer 49

Bipyridines

Question 50

POSITIVE INOTROPIC DRUG USED IN HF

Answer 50

PDE inh Beta adrenoceptor agonist Cardiac glycoside

Question 51

Inhibit sodium potassium atpase

Answer 51

Digoxin