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Heart Failure > Hf > Flashcards

Hf Flashcards

1
Q

Acute heart failure mgt

A

Furosemide
Dopa and dobutamine
Nitroprusside, ntg, nesiritide
Levosimendan
Conivaptan
Tolvaptan

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2
Q

V1 and V2 receptor - txt : euvolemic hyponat

A

Conivaptan

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3
Q

V2 antagonist - txt: acute heart failure and hyponat

A

Tolvaptan

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4
Q

Beta 2 adrenoceptor blocker
Can be given to diastolic and systolic failure

A

Nevibolol

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5
Q

Given only to patient when diuretics and ace in have failed to control SYMPTOMS OF CHRONIC HF

A

Digoxin

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6
Q

A VENODILATORS
Use in patient with increasing filling pressure and dsypnea

A

Nitrates

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7
Q

Give to the pt with left ventricular dysfunction but no edema
Combined with diuretics as FIRST LINE THERAPY FOR HF

A

Ace in and ARBS

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8
Q

Used in pt with moderate to severe hf

A

Spironolactone and eplerenone

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9
Q

No limitations on ordinary physical act and symptoms occur only with greater than ordinary exercise

A

Class 1

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10
Q

No symp at rest , but fatigue less than ordinary Physical act

A

Class 3

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11
Q

Slight limitations of ordinary act, results to fatigue and palpitations with ordinary activity

A

Class 2

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12
Q

Assoc symptoms even with at rest

A

Class 4

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13
Q

Arteriolar dilators
Txt - pt with fatigue due to dec left ventricular output

A

Hydralazine

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14
Q

Sglt2 Inhi
Reduce hospitalization

A

Empagliflozin

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15
Q

Sglt2 Inhi
Reduce hospitalization

A

Empagliflozin

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16
Q

Glp1 agonist

A

Liraflutide

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17
Q

Glp1 agonist

A

Liraflutide

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18
Q

Neuregulin ggf2 protein
Benefits with HF AND DIABETES

A

Cimaglermin

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19
Q

Beta ADRENOCEPTOR BLOCKER

A

M C B N

METOPROLOL
CARVEDILOL
BISOPROLOL BUCINDOLOL
NEBIVOLOL

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20
Q

ANP AND URODILANTIN

A

Carperitide and ularitide

Bosentan and tezosentan

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21
Q

Orally active competitive inhibitors of endothelin

A

Bosentan and tezosentan

22
Q

Approved for PULMUNARY HTN

SE: teratogenic and hepatotoxic

23
Q

Bnp

A

Nesiritide
Sacubitril

24
Q

Useful diagnostic or prognostic test

25
Q

Synthetic form of Bnp
Use in acute cf

A

Nesiritide

26
Q

Moa: increase cgmp in sm and reduce venous and arteriolar tone

With SE : excessive hypotension

A

Nesiritide

27
Q

Prodrug - metab to ACTIVE NEPRILYSIN INHI plus an ARB ( valsartan )

Approved for HF-rEF

A

Sacubitril

28
Q

Vasodilators

A

H I

HYDRALAZINE
ISDN

29
Q

Provide reduction in preload ( venodilation) and reduction in afterload (arteiolar dilation)

A

Vasodilator

30
Q

Long term vasodilation, reduce damaging remodeling of the heart

A

HYDRALAZINE AND ISDN

31
Q

Venous dilator, REDUCE PRELOAD
Txt- pt with high FILLING PRESSURE with dyspnea — pulmonary congestion

32
Q

Arteriolar dilator, reduce afterload , inc forward CO

TXT- pt with low lef ventricular output complaining fatigue

A

Hydralazine

33
Q

Arbs

A

C A L

CANDESARTAN
ALISKERIN
LOSARTAN

34
Q

Renin inh approved for hypertension

35
Q

First line in mgt of pt with LEFT VENTRICULAR DYSFUNCTION Without edema

36
Q

Fist line txt - CHRONIC HF by reduce preload and afterload in ASYMPTOMATIC PATIENT

With SE: incessant cough

37
Q

It slows the progression of ventricular dilation thus slow the downward spiral of the heart

38
Q

Reduce peripheral resistance —- reduce afterload

** reduce salt and water retention ( reducing aldosterone secretion ) —— reduce preload

39
Q

Drugs without POSITIVE INOtropic used in HF

A

Diuretics
Ace in
Arbs
Vasodilators
Bnp
ANP
Beta adrenoceptor blocker

40
Q

Steroid deriv
Inhibiting Na/ K ATPase but in addition it FACILITATES SEQUESTRATION OF CA BY THE SR

A

Istaroxime

41
Q

Sensitize the tropinin sys to calcium
Inhibit PDE, cause vasodilation

A

Levosimendan

42
Q

Iv agents - activates cardiac myosin and prolong systole without increasing o2 consumption of the ❤️

A

Omecative mecarbil

43
Q

Beta adrenoceptor agonist

44
Q

B 1 selective ago ( inc camp )
Increase in CO AND DECREASE in VFP

A

Dobutamine

45
Q

CI: pheochromocytoma and tachyarrythmia

A

DOBUTAMINE

46
Q

Stimulation of peripheral posjuctional D1 and prejunctional D2 receptors

Use in hf if need mag increase ng BP

47
Q

PDE INH

A

Bipyridines

**
Milrinone
Inamrinone
Amrinone

48
Q

Inhibits PDE 3 and less like to cause bone marrow and liver toxicity

49
Q

Incre inward calcium influx in ❤️ during AP

A

Bipyridines

50
Q

POSITIVE INOTROPIC DRUG USED IN HF

A

PDE inh
Beta adrenoceptor agonist
Cardiac glycoside

51
Q

Inhibit sodium potassium atpase

Heart Failure (3 decks)

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