Herpetic encephalitis, meningoencephalitis and encephalomyelitis

Question 1

what type of inflammation is herpetic encephalitis?

Answer 1

nectrotising hemorrhagic inflammtion affecting specially the temporal lobe

Question 2

what is the pathophysiology of herpetic encepahlitis ?

Answer 2

through primary infection of HSV1 and HSV2 by mucosal or dermal penetration
reactivation of viral dna in trigeminal ganglion and axonal spreading to the frontal and temporal lobe

Question 3

what are the symptoms for herpetic encephalitis ?

Answer 3

fever and headache
change in personality
seizure due to raised intrcranila pressure

Question 4

how do we diagnose herpetic meningitis ?

Answer 4

MRI - for specific lesions
frontotemporal hyperintensive lesion
enedematous parenchyma

Question 5

what is the therapy for herpetic encephalitis ?

Answer 5

antiviral therapy immediatly

intracranila pressure therapy - mannitol and glucocorticoids