Herpes Viruses

Question 1

Location of HSV 1 (ganglion) and infection

Answer 1

trigeminal-commonly above the waist

Question 2

Location of HSV 2

Answer 2

sacral ganglion

Question 3

Herpes common in thumb sucking, gynecologist, and dentist

Answer 3

Herpetic Whitlow

Question 4

virus that reactivates down Va to the cornea

Answer 4

Herpetic Keratoconjunctivitis

Question 5

No lesions, still contagious?

Answer 5

Yeah

Question 6

Rates of shedding higher with 1 or 2

Answer 6

2

Question 7

More likely teratogen, 1 or 2?

Answer 7

2

Question 8

When is herpes passed on

Answer 8

birth

Question 9

Causes chicken pox and shingles

Answer 9

VZV

Question 10

Vaccine for VZV is…

Answer 10

live attenuated

Question 11

primary acute VZV

Answer 11

chicken pox

Question 12

Recurrent VZV

Answer 12

shingles

Question 13

more painful of VZV diseases

Answer 13

shingles > Chicken pox

Question 14

successive lesions are

Answer 14

chicken pox

Question 15

aspirin for chicken pox? Why or why not

Answer 15

No, reyes –> brain edema/fat deposits

Question 16

longer, chicken pox or shingles

Answer 16

shingles ~ 1 month

Question 17

Causes mono

Answer 17

EBV

Question 18

Causes hairy oral leukoplakia

Answer 18

EBV

Question 19

causes burkitts

Answer 19

EBV

Question 20

Downey cells

Answer 20

EBV

Question 21

Cell response that leads to mono, oral hairy, Burkitt’s, and normal

Answer 21

Oral hairy –> lack cell-mediated response
Burkitt’s –> poor cellular response
Normal –> asymptomatic
Vigorous response –> mono

Question 22

Associated with non-specific Abs (also, these are called what)

Answer 22

Mono-called heterophiles; this is EBV mono b/c it is heterophile +

Question 23

Babies rxns to mono

Answer 23

none, asymptomatic b/c lack robust immune response

Question 24

most at risk for mono

Answer 24

teens (kissing disease), low socioeconomic, in developing countries there is 100% exposure

Question 25

See irregular lymphocytes, it is?

Answer 25

Mono-these are Downey cells caused by EBV

Question 26

Burkitt’s lymphoma, caused by _______, is most commonly found in ?

Answer 26

Young African boys (with malaria)

Question 27

Burkitt’s lymphoma is associated with what other disease

Answer 27

malaria

Question 28

Burkitt’s is cancer of what (cell type)

Answer 28

B cells

Question 29

Swollen jaw could be

Answer 29

Burkitt’s lymphoma caused by EBV

Question 30

Hairy oral leukoplakia vs Thrush (candasis)

Answer 30

cannot be scraped off, thrush can

Question 31

High fever and then a maculopapular rash in babies is probably caused by

Answer 31

HHV-6

Question 32

Giant cells/Owl’s eye inclusion bodies is diagnostic of what

Answer 32

Cytomegalovirus!!! Not Kaposi’s!

Question 33

Heterophile (-) mono caused by

Answer 33

cytomegalovirus

Question 34

opportunistic in organ transplant patients (hint, it is a herpes virus)

Answer 34

cytomegalovirus