Herpes Simplex Keratitis Flashcards

1
Q

What is Herpes Simplex Keratitis (HSK)?

A

The most common leading cause of corneal blindness in developed countries, presenting as a dendritic ulcer.

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2
Q

What are common causes of HSK?

A
  • Stress
  • Pregnancy
  • UV light exposure
  • History of cold sores
  • Systemic illnesses
  • Poor general health/fatigue
  • Immunodeficiency
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3
Q

What are the key signs of HSK?

A
  • Punctate lesions coalescing into a dendriform pattern
  • Opaque cells in a stellate pattern
  • Reduced corneal sensitivity
  • Conjunctival redness
  • Amoebic or geographic ulcer
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4
Q

What are the common symptoms of HSK?

A
  • Photophobia
  • Foreign body sensation
  • Reduced visual acuity
  • Redness
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5
Q

When is an urgent referral to an ophthalmologist required for HSK?

A

For acute or recurrent epithelial HSK with no stromal involvement.

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6
Q

When should HSK be considered an emergency?

A

If the patient is a child, contact lens wearer, has viral retinitis, or if the condition is bilateral.

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7
Q

How is the virus causing HSK confirmed?

A

By isolating the virus from a corneal swab or biopsy.

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8
Q

What antiviral medications are used to treat HSK?

A
  • Aciclovir 3%, used 5 times daily
  • Ganciclovir 0.15%
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9
Q

What surgical options are available for severe HSK?

A

Surgical removal of damaged tissue or penetrating keratoplasty in cases with scarring.

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10
Q

What is the prognosis for HSK?

A

Prognosis is usually good but depends on the severity and number of recurrences of the disease.

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11
Q

What type of ulcer is characteristic of HSK?

A

Dendritic ulcer.

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12
Q

Why should steroids never be given for HSK?

A

Steroids can exacerbate the condition.

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13
Q

What is a dendritic ulcer?

A

A branching ulcer on the cornea caused by the herpes simplex virus, characteristic of HSK.

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14
Q

What pattern do opaque cells form in HSK?

A

Stellate (star-shaped) pattern.

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15
Q

How does HSK affect corneal sensitivity?

A

It reduces corneal sensitivity.

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16
Q

What is the role of penetrating keratoplasty in HSK?

A

It is used in cases with scarring to restore vision.

17
Q

What are the risk factors for recurrent HSK?

A
  • Stress
  • UV light exposure
  • Immunodeficiency
  • Poor general health
18
Q

What are amoebic or geographic ulcers in HSK?

A

Larger, irregular corneal ulcers seen in more severe cases of HSK.

19
Q

What systemic conditions can trigger an HSK flare-up?

A

Systemic illnesses or immunodeficiency.

20
Q

How often should aciclovir be applied in HSK treatment?

A

5 times daily.