Herpes Simplex Flashcards
Name the 4 pathogenic Herpes viruses.
HSV (herpes simplex)
VZV (varicella zoster)
EBV (epstein-barre)
CMV (cytomegalovirus)
Which herpes simplex virus infects the mouth and lips.
HSV-1 : the majority of people get this.
Which herpes simplex virus infects anogenital
HSV-2: 8/10 peopel show no Sx with this.
What is the name of the herpes virus that can infect fingers of healthcare workers?
Herpes Whitlow
What does the herpes simplex virus look like?
Grouped small uniform vesicles on erythematous base that erode.
What typically precedes the appearance of vesicles in herpes simplex?
1-2 days of tingling, burning, itching.
low grade fever and malaise
T/F : commonly recurs in the same area.
T
What factors may predispose you to getting herpes simplex?
UV light, trauma & systemic changes may predispose
How long does viral shedding last and how is a person is herpes simplex contagious?
Viral shedding occurs until crusted in 4 -7 days, contagious until lesions healed
T/F : herpes simplex usually leaves scars once it is healed.
F. it typically does not leave scars.
How long is the herpes simplex infection course?
5-14 days per episode.
How do you diagnose herpes simplex?
By clinical signs & symptoms, PCR or culture
How do you treat herpes simplex?
Symptomatic – goal is to relieve discomfort and promote healing
Antivirals (Acyclovir (zovirax) Available in topical, oral or IV, depending on severity)
Can you spread herpes simplex while asymptomatic?
yes.
T/F : Herpes simplex is a self limited infection.
T
What does the antiviral medication (acyclovir MOA) help in herpes simplex?
decrease viral shedding, new lesion formation & promotes healing
What are some complications with herpes simplex?
- Can disseminate in immunocompromised
- Pregnant women
- Neonatal disseminated disease
What are we most concerned about in pregnant women with herpes simplex?
We worry most about HSV-2 that develops late in pregnancy.
What are the differential diagnosis of herpes simplex?
Herpes Zoster
Impetigo
Apthous ulcers
