Herpes Simplex Flashcards

1
Q

Name the 4 pathogenic Herpes viruses.

A

HSV (herpes simplex)
VZV (varicella zoster)
EBV (epstein-barre)
CMV (cytomegalovirus)

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2
Q

Which herpes simplex virus infects the mouth and lips.

A

HSV-1 : the majority of people get this.

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3
Q

Which herpes simplex virus infects anogenital

A

HSV-2: 8/10 peopel show no Sx with this.

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4
Q

What is the name of the herpes virus that can infect fingers of healthcare workers?

A

Herpes Whitlow

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5
Q

What does the herpes simplex virus look like?

A

Grouped small uniform vesicles on erythematous base that erode.

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6
Q

What typically precedes the appearance of vesicles in herpes simplex?

A

1-2 days of tingling, burning, itching.

low grade fever and malaise

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7
Q

T/F : commonly recurs in the same area.

A

T

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8
Q

What factors may predispose you to getting herpes simplex?

A

UV light, trauma & systemic changes may predispose

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9
Q

How long does viral shedding last and how is a person is herpes simplex contagious?

A

Viral shedding occurs until crusted in 4 -7 days, contagious until lesions healed

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10
Q

T/F : herpes simplex usually leaves scars once it is healed.

A

F. it typically does not leave scars.

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11
Q

How long is the herpes simplex infection course?

A

5-14 days per episode.

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12
Q

How do you diagnose herpes simplex?

A

By clinical signs & symptoms, PCR or culture

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13
Q

How do you treat herpes simplex?

A

Symptomatic – goal is to relieve discomfort and promote healing

Antivirals (Acyclovir (zovirax) Available in topical, oral or IV, depending on severity)

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14
Q

Can you spread herpes simplex while asymptomatic?

A

yes.

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15
Q

T/F : Herpes simplex is a self limited infection.

A

T

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16
Q

What does the antiviral medication (acyclovir MOA) help in herpes simplex?

A

decrease viral shedding, new lesion formation & promotes healing

17
Q

What are some complications with herpes simplex?

A
  1. Can disseminate in immunocompromised
  2. Pregnant women
  3. Neonatal disseminated disease
18
Q

What are we most concerned about in pregnant women with herpes simplex?

A

We worry most about HSV-2 that develops late in pregnancy.

19
Q

What are the differential diagnosis of herpes simplex?

A

Herpes Zoster
Impetigo
Apthous ulcers