Heritable Disorders

Question 1

Ichthyosis Vulgaris

Answer 1

• immersion in bath and oils followed by an emollient cream, humectant cream, or creams/oil containing
urea or α- or β-hydroxy acids
• intermittent systemic retinoids for severe cases

Question 2

Neurofibromatosis (Type I; von Recklinghausen’s Disease)

Answer 2

refer to orthopedics, ophthalmology, plastics, and psychology
• follow-up annually for brain tumours (e.g. astrocytoma)
• excise suspicious or painful lesions

Question 3

Vitiligo

Answer 3

sun avoidance and protection
• topical calcineurin inhibitor (e.g. tacrolimus, pimecrolimus) or topical corticosteroids
• PUVA or NB-UVB
• make-up
• “bleaching” normal pigmented areas (i.e. monobenzyl ether of hydroquinone 20%) if widespread loss of
pigmentation