Herbal Medicines Flashcards
Echinacea intended use
decreasing duration and intensity of colds
Echinacea proven effects
immune modulating
anti-inflammatory
increases numbers of immunologic blood cells
Contraindications of echinacea
avoid with patients with immune deficiencies or those on immunosuppressants
Ginkgo biloba current uses
imrove memory
tx/prevention of alzheimers
tx/prevention of peripheral vascular disease
Ginkgo biloba two unique adverse effects/drug interactions
may have anti-platelet actions
uncooked seeds contain a toxin that may induce seizures in susceptible individuals
Garlic primary uses
atherosclerosis
high cholesterol
hypertension
Garlic most studied constituent
ALLICIN
Proposed mechanisms of garlic
inhibition of ACE
Increased NO availability
Increased H2S production
Adverse effects of garlic
INCREASED BLEEDING
discontinue 7 days prior to surgery
Ginseng primary uses
support overall health and immune system, well being, stamina, MENTAL AND PHYSICAL PERFORMANCE
Adverse effects of ginseng
CNS stimulation
Hypertension
Auto-immune disorers
Anti-platelet activity
Milk Thistle primary uses
LIVER DISEASE
cirrhosis, drug induced hepatotoxicity, hepatitis
Milk thistle mechanism of action proposed
preventing excessive collagen accumulation
St. John’s Wort used primarily as
anti-depressant
St. Johns Wort mechanism
inhibiting re-uptake of serotonin
St. Johns Wort adverse interactions
CAN INDUCE P-450 SYSTEM
DECREASES SERUM CONCENTRATIONS OF OTHER DRUGS
may have caused transplant rejection
Saw palmetto primary use
BENIGN PROSTATIC HYPERPLASIA
Glucosamine and Chondroitin primary uses
OSTEOARTHRITIS
Melatonin primary use
insomnia, sleep aid
Adverse effect of melatonin
DECREASES SPERM QUALITY IN MEN
DECREASES LUTEINIZING HORMONE IN WOMEN
Butterbur primary use
MIGRAINE
Feverfew primary use
migraines
Feverfew adverse effects
mouth ulceration
uterine contractions
coagulation effects
Coenzyme Q10 primary uses
REDUCTION OF STATIN INDUCED MYOPATHY
statins decreased serum CoQ10 levels
HTN, ischemic heart disease, migraine, neurodegenerative diseases
CoQ10 Adverse effects
SHOULDN’T BE USED IN PATIENTS TAKING WARFARIN
Fish oil primary uses
hypertriglyceridemia
CV disease
Glucosamine/Chondroitin adverse effect
bleeding