herbal Flashcards

1
Q

Dshea
Dietary Suppliement Health & Education Act
1994

A
  • increased phytochemicals for consumption
  • distinguished dietary suppliment from food additiivies
  • Limits FDA: allow exemption of premarket approval for supplements
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2
Q

View points of suppliment users

A
  • increasing
  • not consider herbal
  • herbs contain active drugs
  • dont link adverse health events
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3
Q

What percentage of patients revel the use suppliments

A

40%

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4
Q

Studies that serve as initial indicators of possible herb drug interactions but not establish cause

A

case report

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5
Q

studies that assess various effects of botanicals using human subject

A

prospective in vivo studies

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6
Q

Studies that show effects of phyochemicals on purified enzymes/transporters

A

in vitro screens

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7
Q

Area of the body where herbs can change drug metabolizing enzymes are found

A

small intestine and liver

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8
Q

herbs can modulate drug transport primarily found in what areas of the body

A

small intestin, bbb, liver

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9
Q

most important enzymes

A

cyp3A4, cyp2d6, cyp2c9, cyp 1A2

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10
Q

St. Johns Wort

A

Indication: Antidepressive
Efficacy good
drug interaction risk highg (render most drugs ineffective)
-effects transplants recieving cyclosporin

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11
Q

means other than conventional medicines to treat

A

alternative medicines

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12
Q

Herbs, essential oils, and neti pots to treat is example of

A

alternative medicines

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13
Q

using both conventional and other means to treat without recommendation of providers is called

A

complimentary medicines

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14
Q

Using prescribed antibiotics, along with essential oils and neti pot to treat is example of

A

complimentary medicine

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15
Q

prescribed use of conventional medicine along with other means for treatment is known as

A

integrative medicine

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16
Q

APRN prescribes antibiotics, AND essential oils with neti pot to treat is example of

A

integrative medicine

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17
Q

Benefits of Tai Chi

A
helps Parkinsons balance
decrease osteoarthritis pain
decrease back pain and fibromyalgia
increase concentration
decrease depression
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18
Q

benefits of yoga

A

improves lymphedema well being

19
Q

Acupuncture benefits

A

alleviate abnormal blood flow (chee)

may help with N/V; hot flashes; pain, and psycho disorder

20
Q

Mindfulness benefits

A

reduce stress
reduce cancer fatigue
weightloss

21
Q

Essential oils benefits

A

symptom management

not FDA approved for cure of specific diagnosis

22
Q

Describe Reiki

A

energy medicine; moving blocked energy from chakra center

identify hot and cold centers

23
Q

Describe Sound centers

A

singing bowls used to open chakra

24
Q

Describe crystal healing

A

crystals are used to open chakra centers

25
Q

Describe Ayurveda

A

supplements high in heavy metals and arsenic and lead; mind body medicine living in tune with natures

26
Q

side effects of use of ephedra

A

cardiovascular and central nervous system events

27
Q

What is Ma-Huang

A

The ancient Chinese ephedra herb

28
Q

catechins, xanthones, and tannins can be seen in caffeine natural sources to inhibit COMT and MAO to potentiate what activity

A

sympathomimetic

29
Q

Ephedra and Caffeine can lower blood flow to

A

cerebral areas

30
Q

The difference in herbal supplements in single vs multi-ingredient supplements

A

the multi ingredient suppliments can cause toxic reactions

31
Q

Licorice root Interactions

A

Glycyrrhiza Glabra
Interaction mxn: sodium retention, K depleting
Interacts with: diuretics and antiarrhythmic

32
Q

When herb induce cyp or P-gp what levels of drug are suspected in body

A

reduced

33
Q

When herb inhibits cyp or P-GP what levels of durg are suspected in body

A

increased

34
Q

Patient with recent renal transplant asks about restarting St. Johns Wart. The APRN suggests

A

can not restart St. John Wart due to interaction with cyclosporin and potential of organ failure

35
Q

Chemical in St john wart responsible for interaction

A

hyperforin

stronger than rifampin in receptor affinity

36
Q

Goldenseal information

A

Cold, URTI, mask urine RX screens
Efficacy: poor
high interaction risk inhibits cyp3A4 and cyp2D6

37
Q

How can Goldenseal increase the efficacy of a smaller dose of quinine

A

quinine is a substrate of CYP 3A4, goldenseal binds to 3A4

38
Q

MDP containing botanicals can interfere with which cyp

A

CYP3A4

39
Q

how does MDP contiaining Schizandra has what effect on tacrolimus? where can Schizandra be found

A

increases absorption

weight-loss supplement

40
Q

Resveratrol effects what cyp450

A

decrease cyp2C9 activity

41
Q

resveratrol has what effect on diclofenac

A

diclofenac levels increase

42
Q

Green tea has what effect on nadolol

A

catechins in green tea decreases effects absorption

43
Q

what is a liposome

A

artificial vesicles composed of phospholipid membranes surrounding an aqueous core.
can greatly improve oral bioavailability

44
Q

what is a phytosomes

A

improve stability and shelf life, and improve bioavailability can be improved 2 to 6 fold