Hepatology 3

Question 1

List three methods of medical therapy for hepatic encephalopathy

Answer 1

Dietary modification
Lactulose
(Antibiotics)

Question 2

How is the diet modified to help with hepatic encephalopathy?

Answer 2

Protein modification/restriction

Question 3

List two common anti-oxidants that are used in liver disease

Answer 3

Milk thistle extracts/isolates
S-Adenosyl-L-methionnine (SAMe)

Question 4

List two liver diseases that may benefit from immunosuppression

Answer 4

Chronic hepatitis
Lymphcytic cholangitis

Question 5

What is the mechanism of choleretics?

Answer 5

Alters bile composition
Stimulates bile flow
Modulates inflammatory response in the liver
Modifies apoptosis

Question 6

What is ursodeoxycholic acid used for?

Answer 6

Choleretics

Question 7

Which antimicrobial would you use to treat leptospirosis?

Answer 7

Doxycycline

Question 8

List three consequences of portal hypertension

Answer 8

Secondary shunting
Splanchnic bed oedema - impairs GI perfusion and health; GI haemorrhage
Ascites

Question 9

How would you treat portal hypertension?

Answer 9

Treat cause
Spironolactone +/- Na+ restriction
Avoid GI toxic drugs

Question 10

What is the name of the embyronic vessel that bypasses the liver in the foetus?

Answer 10

Ductus venosus