Hepato-biliary surgery Flashcards
What is the composition of gallstones?
Cholesterol
Pigment
(Mixed) 80%
What are the risk factors for Gallstones?
Old
Female
High cholesterol
Pigment (far east)
Presentation of Gallstones
Asymptomatic
Dyspepsia - flatulent
Biliary colic
What are some of the complications of Gallstones?
Cholecystitis (upper R quadrant pain) Empyema Perforation Mirrizi's Syndrome Gallstone ileus
What is Mirrizi’s syndrome?
Jaundice associated with pain, fever and rigors
What is choledocholithiasis?
Presense of gallstones in the common bile duct
Symptoms of obstructive jaundice
Pain
Dark Urine
Pale stool/steatorrhoea
Pruritus
What is Charcot’s triad?
PAIN
JAUNDICE
RIGORS
Choledocholithiasis is a common cause of what?
Post-cholecystectomy pain
What are the rare but serious complications of choledocholithiasis
Ascending cholangitis (biliary tree sepsis) Acute pancreatitis
Investigations for gallstones
LFTs Amylase, Lipase WCC USS CT Scan MRCP/ERCP PTC
Treatment for asymptomatic gallstones
None
What is the gold standard treatment for gallstones
Laparoscopic cholecystectomy
How are cystic bile duct stones managed?
Laparoscopic/open exploration of the Common bile duct
ERCP
What are the common congenital causes of biliary tract disease?
Biliary atresia
Choledochal cysts
What are the common causes of benign biliary tract stricture?
Iatrogenic
Gallstone-related
Inflammatory
What classification is used for iatrogenic bile duct injury?
Strasberg classification
What is primary sclerosing cholangitis?
Scarification of the biliary tree
PSC increases the risk of what?
Cholangiocarcinoma
The majority of cholangiocarcinomas occur where?
Hilar extrahepatic (67%)
Jaundice can be caused by which cancers of the biliary tract?
Cholangiocarcinoma
Cancer of the pancreatic head
Risk factors for cholangiocarcinoma?
>80 PSC Congenital cystic disease Biliary-enteric drainage Contras Hepatolithiasis
What are the three types of intrahepatic cholangiocarcinoma?
Mass forming
Peri-ductal
Intra-ductal
Presentation of cholangiocarcinoma
Painless obstructive jaundice
Itching
Non-specifics
Investigations for cholangiocarcinoma?
Radiology (USS, EUS, MRCP, FDG PET)
ERCP
Cytology
Management of cholangiocarcinoma
SURGERY
Palliative
How is gallbladder cancer detected early?
Incidental in gallstones
Treatment options for ampullary tumours
Excision