Hepatitis Viruses - Part 2

Question 1

HDV is in 50% of HBV carriers (T/F)

Answer 1

True

Question 2

HDV morphology

Answer 2

Circular single stranded RNA

Surrounded by HBsAg

Question 3

HDV - Modes of Transmission

Answer 3

Percutanous exposures
- injecting drug use

Permucosal exposures
- sexual contact

Question 4

2 forms of infection - HDV

Answer 4

1)Co infection : Simultaneously HBV+ HDV

      picture of acute HBV infection

      superimposed HDV serological pattern 

      short lived , transient

  2)Super infection : Chronic HBV with superadded

      HDV infection 

      Prolonged replication leading to chronic

      infection

Question 5

2 forms of infection - HDV

Answer 5

1)Co infection : Simultaneously HBV+ HDV

      Acute HBV infection

      Superimposed HDV serological pattern 

      Short lived , transient

  2)Super infection : Chronic HBV with superadded

      HDV infection 

      Prolonged replication leading to chronic

      infection

Question 6

Serology Testing - Hepatitis

Answer 6

HBS Ag - Found in Surface of virus 
                \+ve = infection 
HBE Ag - Found in envelope of virus
                \+ve = > in infectivity and > in replication 
HBC Ag - Found in capsid --C for core 
                 Not measured 
Anti HBS : +ve = cured/vaccinated
Anti HBC : IgM +ve - acute 
                  IgG +ve - chronic
Anti HBE : +ve = < in infectivity < in replication