Hepatitis Viruses - part 1 Flashcards
HAV, HBV, HEV
Viral hepatitis - types
HAV, HBV, HCV, HDV, HEV
Hepatitis as a complication
- Yellow fever, CMV, EBV, HSV
- Entero, Rubela, Adeno
Hepatitis A common name
Infectious
Naked, RNA, picornavirus is the virus structure of ?
Hepatitis A
Transmission - Hep A
Fecal-oral
Incubation period - Hep A
Short
Usual onset - Hep A
Abrupt
Mild or asymptomatic severity for which virus?
Hep A
Very low mortality rate for which virus?
Hep A
Chronicity/carrier state for Hep A?
None
Hep A has other disease associations (T/F)
False
The common name for Hepatitis B is serum (T/F)
True
Virus structure for Hep B
Envelope, DNA, hepadnavirus
The transmission of Hep B is fecal oral (T/F)
False; parenteral and sexual
Incubation period - Hep B
Long
The usual onset of Hep B is?
Insidious (gradual)
The severity of Hep B is occasionally severe (T/F)
True
Mortality rate - Hep B
Low
Presence of chronicity/Carrier state - Hep B
Yes
Hep B has other disease associations which are?
HCC, Cirrhosis
HCC - explain
Hepatocellular carcinoma - primary liver cancer
In chronic infection for Hepatitis, the virus continues to replicate in liver cells causing continued immune response leading to cell death.
Since the liver regenerates, mitosis occurs consistently.
Also due to cell death, scar tissue forms leading to high chance for cirrhosis.
With higher rates of mitosis, replication must occur more often and this leads to higher chances of mutations = cellular dysplasia (abnormal development of cells+tissues) causing HCC
Hepatitis C common name
Posttransfusion non A, non B
(Hepatitis was found in some persons receiving blood transfusions; HepA is rare to contract from post transfusion and Hep B is usually asymptomatic. Cases of non A, non B Hepatitis is referred to as Hep C)
Incubation period of Hep C is short (T/F)
False; it is long
Usual onset of Hep C is abrupt (T/F)
False; it is insidious