Hepatitis Viruses

Question 1

Hepatitis with fecal-oral transmission

Answer 1

A, E
vowels hit your bowels yo
contaminated food

Question 2

Sexually Transmitted Hepatitis

Answer 2

B, C, D

Question 3

Common Presentation (Hep)

Answer 3

fever, jaundice, inc ALT/AST, RUQ pain

Question 4

HAV (short)

Answer 4

Asymptomatic, Acute, Alone (no carriers)

Question 5

HBV (short)

Answer 5

Blood, Baby-making, Birthing

Question 6

HCV (short)

Answer 6

Chronic, Cirrhosis, Carcinoma, Carrier

Question 7

HDV (short)

Answer 7

Defective virus, Dependent (on HBV)

superinfection means poor prognosis

Question 8

HEV (short)

Answer 8

Enteric, Expectant mothers (high mortality), Epidemic

Question 9

HBsAg
ABeAg
Anti-HBc IgM

Answer 9

Acute HBV infection

Question 10

HBsAg
HBeAg
Anti-HBc IgG

Answer 10

Chronic HBV with high infectivity

Question 11

HBsAg
Anti-HBe
Anti-HBc IgG

Answer 11

Chronic HBV with low infectivity

Question 12

Anti-HBs

Answer 12

vaccinated for HBV

Question 13

HBV incubation period test

Answer 13

HBsAg

Question 14

HBV prodrome, acute disease test

Answer 14

HBSAg (anti-HBc)

Question 15

HBV early convalescence

Answer 15

Anti-HBc

Question 16

HBV late convalescence

Answer 16

Anti-HBs (anti-HBc)

Question 17

Viral hepatitis vs. alcoholic hepatitis liver tests

Answer 17

viral: ALT>AST
alcohol: AST>ALT

Question 18

Which Hepatitis lead to chronic infection?

Answer 18

B,C,D

Question 19

Which Hepatitis are we immunized against?

Answer 19

A,B

Question 20

Which hepatitis usually resolves when infected as a healthy adult but almost always (90%) transform to chronic when transmitted at birth?

Answer 20

HBV

Question 21

Icteric phase of hepatits presentation

Answer 21

dark urine- Coca Cola
light feces
jaundice
pruritis
7-28 days after

Question 22

Acute hepatitis lab test always shows what?

Answer 22

increased aminotransferases

look at INR for marker of severity

Question 23

Most common Hep viruses in USA

Answer 23

B > A > C

Question 24

Fulminant Hepatitis

Answer 24

hepatic failure within 8 weeks of onset of acute hep
hepatic encephalopathy and prolonged PT
hepatic necrosis on histo

Question 25

Chronic viral hepatitis definition

Answer 25

elevated aminotransferase and/or viral markers present for >6 months liver firbosis, cirrhosis, hepatocellular carcinoma

Question 26

HBV disease progression

Answer 26

``` Chronic Cirrhosis Liver Failure Liver Cancer Need transplant or die ```

Question 27

HBV disease progression

Answer 27

``` Chronic Cirrhosis Liver Failure Liver Cancer Need transplant or die ```

Question 28

HAV treatment

Answer 28

supportive care- 3 months till improvement PREVENT with immune globulin pre-post exposure vaccine

Question 29

For which Hepatitis should you be concerned about genotype?

Answer 29

HCV

Question 30

Hepatitis extrahepatic complication

Answer 30

cryoglomulinemia autoimmune disease- thyroid glomerular disease

Question 31

Hepatitis superinfection

Answer 31

previouslt infected with HBV then superinfected with HDV | high risk for severe chronic liver disease

Question 32

HEV complications

Answer 32

Neuro- GBS, parsonage tuner syndrome, mononeuropahty | asymptomatic

Question 33

HEV treatement

Answer 33

ribavirin for symptoms otherwise monitor

Question 34

signs of icteric phase

Answer 34

dark urine light feces jaundice pruritis

Question 35

what is fulminant hepatitis?

Answer 35

hepatic failure within 8 weeks of acute hepatitis | diagnose by presence of hepatic encephalopathy and prolonged PT

Question 36

for which hepatitis can immune globulin be give prophylactically for travelling or personal contacts?

Answer 36

HAV

Question 37

chronic active vs. persistent hepatitis

Answer 37

active: HCC, ESLD, cirrhosis persistent: polyarteritis nodosum, glomerulonephritis