Diseases Of The Esophagus Flashcards
Boerheave Syndrome
Transmural tear in the esophagus Career bulimic or alcoholic; violent retching CXR-Air in mediastinum Sounds like rice crispies Surgical emergency
Eosinophilic esophagitis
Path: asthma, allergies, atopy
Food allergens lead to dysphasia, heartburn, and strictures
Dx: EGD Bx >15eos
Tx: trial PPI then oral aerolized steroids
Esophageal stricture
Path: lye ingestion, acid reflux
Pt: GERD, dysphagia, weight loss
Dx: barium is symmetric
Tx: PPI, dilation
Esophageal varices
Path: portal HTN, dilated submucosal veins in lower 1/3
Pt: cirrhotic, alcoholic, upper GI bleed
Dx: EGD
Tx: octerotide (cirrotics), balloon, banding, TIPS, transplant
Ppx: propranolol
Esophagitis causes
PIECE pneumonic Pill induced Infectious Eosinophilic Caustic G(E)RD
Most common causes of infectious esophagitis and their treatments
Candida- fluconazole
HSV- val/a cyclovir (punched out ulcers)
CMV- val/a cyclovir (linear ulcers)
HIV- HAART
Mallory Weiss Syndrome
Path: superficial mucosal tear at gastroesophageal junction due to severe vomiting, hematemesis
Pt: weekend warrior alcoholic, bulimic
Dx: EGD
Tx: self-limiting
Plummer-Vinson Syndrome
Pt: triad dysphagia, iron def anemia, esophageal webs
Dx: see webs on barium
Tx: screen for cancer, more likely to get SCC esophagus
PLUMBERS DIE
Scleroderma
Path: collagen deposition, LES cant contract, smooth muscle atrophy Pt: acid reflux, dysphagia Dx: manometry, barium, EGD w Bx Tx: PPI Serology to confirm path
CREST SYNDROME
Barrett esophagus
Replacement of nonkeratinized stratified squamous epithelium with intestinal epithelium (nonciliated columnar) in distal esophagus.
Assoc: GERD, esophagitis, esophageal ulcers, increased risk of esophageal adenocarcinoma
The AABCDEFFGH of esophageal cancer
Achalasia Alcohol- SCC Barrett- adenocarcinoma Cigarettes Diverticula (Zenker)- SCC Esophageal web- SCC Familial Fat (obese)-adenocarcinoma GERD- adenocarcinoma Hot liquids - SCC
Achalasia
Path: absent myenteric plexus, LES cant relax
Pt: progressive dysphagia, food gets stuck at GE junction
Dx: barium shows dilated esophagus (birds beak) with distal stenosis
Manometry tells us what type
Tx: myotomy
Achalasia may arise secondary to
T. Cruzi infection (Chagas disease)
Malignancies
Diffuse esophageal spasms
Path: crazy contractions
Pt: MI like feeling in chest
Dx; r/o ACS, then barium, manometry, EGD Bx
Tx: Calcium channel blocker and nitrates as needed
Dysphagia: motility and mechanical. Which is progressive?
Mechanical dysphagia shows progressive- first solids, then liquids