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Immunology and Serology > Hepatitis Testing > Flashcards

Hepatitis Testing Flashcards

1
Q

This is “s” means in HBsAg?

A

Surface Antigen

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2
Q

This is how you contract HBV?

A

Blood

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3
Q

What type of specimen is preferred?

A

Serum

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4
Q

These are how you interpret resutls?

A

Reactive
Non-Reactive
Invalid

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5
Q

This is the major agent of chronic hepatitis and liver disease in the word?

A

Hepatitis C

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6
Q

This is the structure of Hepatitis C?

A

Enveloped Positive-Sense, Single Stranded RNA

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7
Q

This is the principle for HIV and HPV testing?

A

Rapid Chromatographic Immunoassay

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8
Q

This is the test for HCV?

A

Anti-HCV Test

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9
Q

This is the recommended confirmatory test done for HCV?

A

Nucelic Acid Testing

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10
Q

This is the reason why you can never get HBsAg and Anti-HBs at the same time?

A

HBsAg indicated a current infection and Anti-HBS indicates immunity.

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11
Q

This is the titer that indicates you are immune to Hepatitis?

A

10

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12
Q

These are the two acrquired types of immunity?

A

Passive and Active

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13
Q

Passive is mostly acquired through?

A

Antibodies, natural and artificial

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14
Q

Active is mostly acquired through?

A

Antigens, natural and artificial

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15
Q

This is the immunoglobulin that can penetrate through the placenta?

A

IgG

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16
Q

This is the immunoglobulin that is tranferred through breast milk?

A

IgA

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17
Q

This is the screening test for HBV that is suitable for pregnant women?

A

HBsAg Test

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18
Q

This is the components inside the test band on HBsAg?

A

Mouse monoclonal Anti-HBs and Colloid Gold Conjugate

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19
Q

This is the sequence that happens to the antibodies, antigens, and anti-antiboies in HBsAg test line?

20
Q

This is how much serum is dispened in the HBsAg device?

21
Q

This is the amount of minutes before interpretting test kits HIV and HPV Chromatographic Immunoassay Kits?

A

20 Minutes

22
Q

This is the amount of serum placed in the square well of the Anti-HAV test kit?

23
Q

How much assay diluent must be added to the round well in the HAV test kit?

24
Q

What’s the diluent placed in the round well called?

A

Assay Diluent

25
Q

These are the corresponding immunoglobulins for chronic and acute HAV?

A

IgG for Chronic and IgM for Acute

26
Q

This is what the test line in HAV kit is made of?

A

Mouse monoclonal anti-human IgG/IgM

27
Q

This is the marker for acute hepatitis A?

A

IgM Anti-HAV

28
Q

This is the principle in order to diagnose acute hepatitis A?

A

Solid-Phase Antibody Capture ELISA

29
Q

This is the result of natural infection of immunization of hepatitis A?

A

IgG Anti-HAV

30
Q

Principle for diagnosing chronic hepatitis A?

A

Competitive Inhibition ELISA Test

31
Q

This is the sequence of appearance of HBV markers found in the serum?

A

HBsAg
HBeAg
HBcAb
HBeAb
HBsAb

32
Q

Why is HBcAg not found in the serum?

A

It’s found in liver biopsies

33
Q

This is also called the Australian Antigen, it is the first marker to appear and is especially important to screen in donor blood?

A

HB Surface Antigen (HBsAg)

34
Q

This is present during active replication of HBV and is in its highly infectious state?

A

HB Envelope Antigen

35
Q

This is the window period of HBV and indicated current or recent infection?

A

IgM Anti-HBc

36
Q

This specific marker antibody of HBV persists for a lifetime?

A

IgG Anti-HBc

37
Q

This is the HBV marker for convalescence (recovery)?

38
Q

This appears during the recovery period of acute hepatitis B?

39
Q

What disappears after a week or month when Anti-HBs appear?

40
Q

This is the amount of serum needed to provide protective immunity against HBV?

A

> 10 mIU/mL of Serum

41
Q

(+) for IgM Anti-HAV?

A

Acute Hepatitis A

42
Q

(+) for Total Anti-HAV?

A

Recovery from Hepatitis A

Includes the presence of IgG Anti-HAV, which leads to recovery

43
Q

(+) HBsAg,
(+) Total Anti-HBc
(+) IgM Anti-HBc
(-) Anti-HBs

A

Acute Hepatitis B

The presence IgM, HBsAg, and Total Anti-HBs but not Anti-HBs mean it is an acute infection

(No IgG Anti-HBc)

44
Q

(-) HBsAg,
(+) Total Anti-HBc
(+) Anti-HBs

A

Recovery from Hepatitis B

Anti-HBs is the marker for Immunity, so they’re recovering by creating immunity.

45
Q

(+) HBsAg,
(+) Total Anti-HBc
(-) IgM Anti-HBc
(-) Anti-HBs

A

Chronic Hepatitis B or Carrier

No IgMs, so it’s mostly IgGs,

HBsAg means they are currenlty having an infection

46
Q

(-) HBsAg,
(-) Anti-HBc
(+) Anti-HBs

A

Immunity to Hepatitis B

Immunology and Serology (8 decks)

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