Hepatitis E Virus

Question 1

Classification

Answer 1

Family: Hepeviridae

Genus: orthohepevirus

Species: hepatitis E

(Hint: occurs during the day, without clothes)

Question 2

Characteristics

Answer 2

• naked nucleocapsid virus
• +ssRNA
• produces one long polyprotein that is cleaved by viral proteins
• cytoplasmic replication

Question 3

Transmission, pathogenesis and diseases:

Answer 3

- similar to hepatitis A virus in the following ways:
Transmitted by fecal-oral route 
No chronic carrier state
No cirrhosis
No hepatocellular carcinoma

Question 4

Treatment and prevention

Answer 4

• no antiviral therapy and no vaccine