Hepatitis A-E

Question 1

The risk of cirrhosis and hepatocellular carcinoma correlates with serum HBV DNA levels, and a focus of therapy is to suppress them to below 300/mL.
T/F

Answer 1

True

Question 2

Your pt is a 47y/o male heroin addict. He presents with insidious onset of anorexia, nausea, vomiting, malaise and fever. He reports an aversion to smoking and on PE you find an enlarged tender liver and scleral icterus. The blood test shows elevated serum HBsAg. What is your diagnosis?

Answer 2

Hepatitis B

Question 3

T/F: Hepatitis A commonly causes chronic liver disease?

Answer 3

False.

Question 4

Your patient is a 34 y/o female who presents with a low grade fever, anorexia, n/v, and malaise for about 5 days. She tells you she traveled to Southeast Asia about a month ago and enjoyed some delish seafood dishes. What are you starting to suspect, and if you’re right, what lab finding do you expect?

Answer 4

HAV

strikingly elevated AST/ALT levels occur early

Question 5

You’re reviewing a blood test on a patient, and you find Anti-HBs in the serum…what does this indicate?

Answer 5

recovery, noninfectivity, immunity to HBV

Question 6

Hep D only occurs in associated with which other hepatitis?

Answer 6

HBV

Question 7

You have a 23y/o male with a hx of IVDU who comes in to see you because his partner noticed he’s looking “yellow.” He reports no other symptoms. What do you suspect and what is the characteristic lab finding?

Answer 7

Hep C
waxing and waning aminotransferase elevations

Diagnosis: enzyme immunoassay detecting Anti-HCV

Question 8

IgM Anti-HBc is only positive in which state of HBV infection?

Answer 8

acute

Question 9

Anti-HBs are only positive in which two states of HBV infection?

Answer 9

exposure & clearance; immunized

Question 10

HBs only positive in which two states of HBV infection?

Answer 10

acute & chronic

Question 11

The only positive serologic marker in an immunized patient will be what?

Answer 11

Anti-HBs