Hepatitis A and B Flashcards
Hepatitis is transmitted via?
Feco-oral route
Incubation period of hepatitis A?
30 days
What does hepatitis A typically present as?
Icteric attack
Does HAV cause chronic liver disease?
No, unlike HBV and HCV
What is the lab for HAV?
antibody for HAV
Hepatitis A is associated with an elevation in both?
Serum aminotransferase and bilirubin
If bilirubin level remains elevated, what should be suspected?
Cholestaric liver disease
What is the prognosis of hepatitis A?
Complete recovery between 3 months
What is the most effective way of preventing HAV infection?
Sanitation, food safety, immunization practices
What should we give to a person after having been exposed to HAV and unvaccinated?
The HAV immunoglobulin within 2 weeks
Hepatitis B structurally is
Double-stranded DNA, unlike the RNA hepatitis A
Transmission of HBV?
parentally/vertically, or horizontally via sex
In the replication cycle of hepatitis B, cccDNA is formed, what’s that?
It serves as a template for RNA transcription
Name both characteristic histological appearances of hepatitis B
Ground-glass appearance and sanded nuclei
At what point is HBV considered to have progressed to chronic?
When HBV DNA and HBsAg persist in the serum longer than 6 months