hepatitis

Question 1

hep A pathology/etiology

Answer 1

benign self-limited disease, transmitted commonly by the fecal-oral route
replicates in liver
shed in feces
killed by thorough cooking
does not cause chronic hepatitis or a carrier state

Question 2

manifestations of hep A

Answer 2

abrupt onset of fever
abdominal pain
mild flu-like symptoms
dark urine
jaundice
asymptomatic in young kids
symptoms last 2 months

Question 3

diagnosis, treatment, complications of hep A

Answer 3

antibodies

vaccine available, supportive care for symptoms, IgG infusion for active disease

Question 4

pathology/etiology of hep B

Answer 4

transmitted by blood products, body fluids, or sexual contact
does not directly kill cell, host’s immune system destroys viral infected cells
rf: drug use, many sex partners, homosexual men, health care workers, birth with infected mom

2-6 month incubation period- asymptomatic

carrier state to chronic hepatitis to cirrhosis to hep D to liver cancer

Question 5

diagnosis and treatment of hep B

Answer 5

HBV antigens/antibodies

supportive care
hepatitis immunoglobulin given to exposed person
immunization

Question 6

pathology/etiology of hep C

Answer 6

2-26 weeks incubation
antibodies develop but are not protective
transmitted via blood, IV drug use or unscreened transfusion in some countries

rf: drug use, many sex partners, sex with infected person, health care workers, birth to infected mom, piercings

Question 7

manifestations of hep C

Answer 7

asymptomatic

Question 8

diagnosis and treatment of hep C

Answer 8

antigen and antibody HCV tests
genotyping

antiviral drugs, current drug therapy

Question 10

pathology/etiology of hep D

Answer 10

an incomplete virus that requires helper function of HBV to replicate, can occur with acute and chronic HBV infection

Question 11

treatment of hep D

Answer 11

none

Question 12

pathology/etiology of hep E

Answer 12

similar to HAV
fecal oral
acute, self limiting infection