Hepatic surgery Flashcards
How does the liver get its blood supply?
Hepatic artery, hepatic portal vein, hepatic vein
What is the function of the liver?
Synthesis proteins (albumin) Synthesis and activation of clotting factors Storage of fats, viatmins, glycogen, copper Degradation of toxins, ammonia, drugs Lipid metabolism Gastrointestinal function Carbohydrate metabolism (glucose) Reticuloendothelial function
What conditions take place if a patient has hepatic insufficiency?
Hypoproteinaemia
Hypoglycemia
Coagulopathy
Hepatic encephalopathy
How should you assess the haemotological system in liver disease and how do you treat before surgery?
Assess clotting times APTT PT
Consider pre-treatment with vitamin K or fresh frozen plasma
Are antibiotics indicated for liver surgery?
Yes
Anaerobic bacteria within the liver, give peri-operative intra-venous antibiotics
Sample areas of the liver for culture
How do you take samples of the liver?
Ultrasound guided FNA, tru-cut biopsy Surgical biopsy (more accurate, potentially safer, laproscopic)
What are the indications for a liver lobectomy?
Neoplasm- benign, malignant
Biopsy/removal of lesion
Liver lobe torsion
abscess
What are the risks of a liver lobectomy and how much of the liver can you remove?
Haemorrhage blood type!
70% of the liver
What are the indications for biliary tract surgery?
Extrahepatic biliary obstruction -choleithiasis (gall stones) -gall bladder mucocele -pancreatits -neoplasia Biliary tract rupture and bile peritonits -trauma -disease process (cholecystitis, inflammation of the gall bladder)
What are the clinical signs of liver disease?
Non-specific Vomiting Icterus annorexia Abdominal pain Hypovolaemia shock (severe EHBO or bile peritonitis)
What parameters show up on haemotology and biochemistry as abnormal in liver disease?
ALT and ALP raised Decreased albumin Increased cholesterol and bilirubin Bile facilitates the absorption of vitamin k Coagulation abnormalities (DIC)
A patient has severe liver dysfunction leading to coagulation abnormalities what can you give to treat this?
Vitamin k-three doses at 0.5-1.5mg/kg s/c or im
Frozen plasma in emergencies 10ml/kg
What can cause bile peritonitis and how is it treated?
Trauma vs biliary tract disease
sterile vs septic
manage peritonitis
treat underlying cause
What are the two types of biliary surgery and what is important to consider?
Cholecystectomy-Surgical removal of the gall bladder
Cholecystoeneterostomy- Gall bladder is joined to the small intestine
Better to preserve the common bile duct rather than the gall bladder
What is the outcome for patients undergoing biliary surgery?
Systemically unwell
intensive post-op care monitor bile leakage, sepsis, SIRS
Significant mortality
cats poor prognosis for neoplasia