Hepatic dysfunction Flashcards

1
Q

what drugs can cause liver injury?

A
  • NSAIDs
  • co-amoxiclav, flucloxacillin
  • anti-TB meds
  • paracetamol
  • methotrexate
  • amiodarone
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2
Q

What med do you use to treat paracetamol poisoning?

A

acetylcysteine

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3
Q

How do you make decisions for when to treat paracetamol poisoning?

A

if blood paracetamol concentrations are above the treatment line on the graph in the bnf

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4
Q

what drugs do you have to be weary about prescribing in someone with hepatic encephalopathy?

A
  • sedating drugs (benzos)
  • agitating drugs (antipsychotics)
  • constipating drugs (opioids)
  • electrolyte disturbing drugs (diuretics)
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