Acronyms

Question 1

What effect does an enzyme inducer have on the concentration of a drug? What’s the acronym for drugs that are enzyme inducers?

Answer 1

increased enzyme activity = decreased drug concentration

PC BRAS
Phenytoin
Carbamazepine

Barbituates (phenobarbital, thiopental)
Rifampicin
Alcohol (chronic excess)
Sulphonylureas (gliclazide, tolbutamide)

Question 2

What effect does an enzyme inhibitor have on the concentration of a drug? What is the acronym for the drugs that are enzyme inhibitors?

Answer 2

Decreased enzyme activity = increased drug concentration

AO DEVICES
Allopurinol
Omeprazole

Disulfiram 
Erythromycin 
Valporate
Isonizad
Ciprofloxacin
Ethanol (acute intoxication)
Sulphonamides (sulfasalazine)

Question 3

Which drugs should be stopped before surgery?

Answer 3

I LACK OP
Insulin

Lithium
Anti-coagulants
COCP/HRT
K-sparing diuretics

Oral hypoglycaemic
Perindropil & other ACE-i

Question 4

what should be your routine for safe prescribing?

Answer 4

PReSCRIBER

Patients name
Reaction (name of drug + reaction)
Sign the chart 
Contraindications (consider from each drug) 
IV fluids (do so if necessary)
Blood clot prophylaxis if necessary
anti-Emetic if necessary 
Relief pain

Question 5

What are the side effects of steroids?

Answer 5

STEROIDS 
Stomach ulcers 
Think skin 
oEdema 
Right and left heart failure 
Osteoporosis
Indigestion 
Diabetes (usually just hyper but can progress to diabetes)
cushings Syndrome

Question 6

What are the contraindications of NSAIDs?

Answer 6

NSAID
No urine (renal failure) 
Systolic dysfunction (heart failure)
Asthma 
Indigestion 
Dyscarsia (blood clots)