Hepatic Disorders Flashcards
liver function study - changes with cirrhosis, liver disease, chronic obstructive jaundice, viral hepatitis
globulins
liver function study - change w/ cirrhosis, chronic hepatitis, edema & ascites
albumin
liver function study - measures the ability of the liver to conjugate & exrete bilirubin
pigment studies
liver function study - abnormal in liver & biliary tract disease; associated w/ jaundice
pigment studies
liver function study - may be prolonged in liver disease; will not return to normal if severe liver damage
prothrombin time
liver function study - ⬆️ in biliary obstruction, ⬇️ in parenchymal liver disease
cholesterol
hepatic dysfunction results from damage to what kind of cells
parenchymal
what is the most common cause of hepatic dysfunction
alcoholism
what are some s/s of hepatic dysfunction
jaundice
ascites
hepatic encephalopathy
what is the bilirubin level with jaundice
> 2.5
obstructed blood flow through the liver resulting in ⬆️ pressure throughout the portal venous system
portal hypertension
what 2 things does portal hypertension result in
ascites
esophageal varices
what can result from ⬇️ albumin synthesis
ascites
which condition causes ascites
cirrhosis w/ portal htn
what procedure can be done to treat ascites
transjugular intrahepatic portosystemic shunt (TIPS)
what is the name of a life threatening complication of liver disease
hepatic encephalopathy
what may cause hepatic encephalopathy
accumulation of ammonia & metabolites in the blood
stage of hepatic encephalopathy - periods of euphoria & lethargy, reversed day/night sleep patterns
stage 1
stage of hepatic encephalopathy - drowsiness, disorientation, mood swings, abnormal eeg
stage 2
stage of hepatic encephalopathy - difficult to arouse, incoherents speech, ⬆️ reflexes, rigid extremities
stage 3
stage of hepatic encephalopathy - comatose, flaccid extremities
stage 4
flapping tremor of hands
asterixis
sweet, slightly fecal odor of the breath
fetor hepaticus
which med would be given to ⬇️ ammonia levels
lactulose