Hep Viruses

Question 1

Which Hep viruses cause Acute LF

Answer 1

Hep A, B , E

Question 2

What causes Chronic Hepatitis

Answer 2

HBV 70%
HCV 20%
NASH 10%
A/w chronic LF

Question 3

Hep A is subclinical?

Answer 3

Yes

Question 4

Hep A what vax?

Answer 4

Killed virus. Traveller’s vaccine

Question 5

which virus is severe in pregnants?

Answer 5

Hep E. 25% fatal, highest risk in 3rd trimester

Question 6

Hep E spread?

Answer 6

water borne, fecal-oral route

Question 7

Progress from Hep B to liver cancer?

Answer 7

Carrier -> Chronic hepatitis-> Cirrhosis -> Liver cancer

Question 8

HEp B transmission?

Answer 8

Needlestick, vertical, sex, blood

Question 9

HBV can cause Polyarteritis nodosa = artery inflammation, glomerulonephritis?

Answer 9

Yes

Question 10

Hep C genetics?

Answer 10

Genetically unstable, has ways to evade host immunity

Question 11

HHV6?

Answer 11

Ubiquitous virus, a/w encephalitis in immunosuppressed

Question 12

HHV6 a/w?

Answer 12

Exanthem subitum (rash)

Question 13

CMV a/w?

Answer 13

infectious mononucleosis, GBS, postnatal hepatitis - hepatomegaly.

Question 14

Treat CMV with?

Answer 14

Ganacyclovir / Valgancylovir

Question 15

CMV looks like what eye?

Answer 15

Owl’s eye inclusion

Question 16

More than 50% of adults have CMV Ab?

Answer 16

Yes

Question 17

Zoster can have?

Answer 17

Shingles - “belt of roses” from thoracic root ganglia
Facial nerve palsy - Ramsay-Hunt syndrome. Geniculate ganglion hit.

Question 18

Complications of Zoster ?

Answer 18

Encephalomyelitis
Post-herpetic neuralgia
Lymphocystic pleocytosis in CSF

Question 19

Varicella?

Answer 19

Vesicles in waves, more in trunk
Skin superinfection
Aseptic meningitis
Neurological syndrome
Post-infectious encephalomyelitis
Pneumonia
Haemorrhage
Arthritis
Congenital Varicella

Question 20

Treat VZV with?

Answer 20

Acyclovir. Live attenuated vaccines

Question 21

MMR transmission?

Answer 21

Aerosol.
Mumps and Rubella vertical too

Question 22

MMR vax?

Answer 22

live attenuated.

Question 23

Spread of Hepatitis viruses?

Answer 23

Hep A + Hep E water borne
Hep B / C / D blood borne

Question 24

Which antibodies are used in vaccines?

Answer 24

HBsAg

Question 25

Which Hep B Ag antibody is marker for infectivity and viremia?

Answer 25

HBeAg

Question 26

Which Anti-Hb Ab protects?

Answer 26

Anti-HBs

Question 27

Which Anti-Hb does not protect?

Answer 27

Anti-HBc

Question 28

W

Which hepatitis viruses transmitted sexually?

Answer 28

Hep B and Hep C