Hemostasis

Question 1

Structure of Blood Vessel is composed of

Answer 1

Vascular Intima (inner)
Vascular Media (middle)
Vascular Adventitia (outer)

Question 2

structure of blood vessel wall that is for production and storage of clotting components

Answer 2

Intima

Question 3

Supporting EC is composed of

Answer 3

Inner elastic lamina (elastin, collagen)

Question 4

Veins: Sub-endothelial EC is composed of

Answer 4

Collagen
Fibroblast

Question 5

Artery: Sub-endothelial is composed of

Answer 5

Collagen
Fibroblast
Smooth Muscle cell

Question 6

Regulates integrity of blood vesselwall

Answer 6

Connective tissue matrix

Question 7

Highly active since it contains hemostatic, coagulation, and fibrinolytic components

Answer 7

Endothelium

Question 8

Normal Phases of Hemostasis

Answer 8

Primary hemostasis (coagulation)
Secondary hemostasis (coagulation)
Fibrinolysis (clot dissolution)

Question 9

2 Major Part of Physiologic Hemostasis

Answer 9

Cellular (PENM)
Plasma Protein

Question 10

Cellular components for Physiologic hemostasis

Answer 10

PENM - Pero Ewan Never Mind
Platelets
Endothelial
Neutrophil
Monocyte

Question 11

Plasma Proteins are for

Answer 11

Coagulation
Dissolution
Anticoagulation (Serine Protease Inhibitions)

Question 12

Process by which there is narrowing of blood vessel and decreased blood flow

Answer 12

Vasoconstriction

Question 13

Reversible; platelet to non platelet surface

Answer 13

Platelet adhesion

Question 14

Platelet receptor in Adhesion process

Answer 14

GP Ib ( F9, F5 )

Question 15

Substance that promotes Platelet adhesion

Answer 15

Von willebrand factor

Question 16

Absence of GP 1b may lead to

Answer 16

Bernard soulier syndrome

Question 17

Characteristics of bernard soulier syndrome

Answer 17

Macrothrombocyte
Giant platelets

Question 18

Absence of subtance for adhesion may lead to what condition

Answer 18

VWF disease

Question 19

Irreversible process; PLATELET TO PLATELET

Answer 19

Aggregation

Question 20

Components needed for Platelet AGGREGATION

Answer 20

GP IIb/IIIa
Calcium
Fibrinogen

(Vwf, Fibronectin)

Question 21

absence of GP IIb/IIIa condition

Answer 21

Glanzzman disease

Question 22

Irreversible; release of discharge contents

Answer 22

Platelet Secretion

Question 23

Alpha granules are also known as

Answer 23

Large granules

Question 24

Alpha granules are

Answer 24

BFF-FVP-PP
B thromboglobulin
Factor V
Factor XI
Fibrinogen
VWf
Protein S
Platelet Factor 4
Plateler derived growth factor

Question 25

Dense granule’s are

Answer 25

ADP
ATP
Calcium
Serotonin

Question 26

ADP + Calcium = (?)

Answer 26

Phospholinase A2

Question 27

What substance does Phospholinase A2 needed to convert

Answer 27

Metabolic Phospholinase

Question 28

Convertion of metabolic phospholipids may lead to the formation of

Answer 28

Arichodonic Acid

Question 29

Substance needed for the conversion of Arichodonic Acid

Answer 29

Cyclooxegenase

Question 30

Cyclooxeganase + Arichodonic Acid = (?)

Answer 30

Prostaglandin endoperoxidase

Question 31

Conversion of Prostaglandin to thromboxane A2 must undergo

Answer 31

Thromboxane synthetase

Question 32

Promotes release of calcium, aggregation, vasocontriction

Answer 32

Thromboxane A2

Question 33

Blocks CYCLOOXEGENASE

Answer 33

Aspirin effect