Hemostasis Flashcards
During in vitro coagulation, which factor is NOT consumed?
Factor VII
Factor XII can be activated by:
contact with negatively charged surfaces
kallekrein
collagen
Fibrinopeptides A and B are by products of:
thrombin acting on fibrinogen
Prothrombin is converted to thrombin by:
a complex of activated Factors X, V, PF3 and calcium
What is true concerning fibrin(ogen) degradation products?
they are cleared by the reticuloendothelial system
they inhibit fibrin formation if present in large amounts
they are formed by the action of plasmin on fibrin(ogen)
Urokinase is a/an:
direct plasminogen activator
Stabilization of the fibrin clot requires adequate amounts of:
Factor XIII
Patients who have a deficiency of AT, Protein C or Protein S may be hypercoagulable because:
these are important inhibitors of coagulation
Fibrin(ogen) degradation products differ from d-dimers because:
d-dimers are fragments from a Factor XIII cross-linked fibrin molecule
Substances that have antiplasmin activity:
alpha 2 macroglobulin
alpha 2 antiplasmin
Plasminogen Activators:
streptokinase
urokinase
vascular endothelium (TPA)
Factor XII name
Hageman factor
Factor VIII name
Anti hemophiliac factor
Factor IX name
Christmas factor
Factor X name
Stuart-Prower factor
