HEMOSTASIS

Question 1

Excess hemostasis

A. poor wound healing
b. clot extension and thrombosis

Answer 1

excess HEMOSTASIS / inadequate FIBRINOLYSIS
- clot extension and thrombosis

inadequate / excess FIBRINOLYSIS
- POOR WOUND HEALING

Question 2

Excess hemostasis

A. POOR WOUND HEALING
B. CLOT EXTENSION AND THROMBOSIS

Answer 2

excess HEMOSTASIS / inadequate FIBRINOLYSIS
- CLOT EXTENSION AND THROMBOSIS

Inadequate HEMOSTASIS / excess FIBRINOLYSIS
- POOR WOUND HEALING

Question 3

Converts plasminogen to plasmin, which plays important role in fibrinolysis

A. PGI2

b. atp
c. thrombomodulin
d. tPA

Answer 3

Tissue Plasminogen Activator (TPA)

- Converts plasminogen to plasmin, which plays important role in fibrinolysis

Question 4

Stimulates vasodilation

A. PGI2

b. atp
c. thrombomodulin
d. tPA

Answer 4

ATP

Stimulates vasodilation

Question 5

Binds and inactivates thrombin and enhances anticoagulant and fibrinolytic action of protein C found in the plasma

A. PGI2

b. atp
c. thrombomodulin
d. tPA

Answer 5

Thrombomodulin
- Endothelial surface receptor for thrombin BINDS AND IANACTIVATES thrombin and ENHANCE anticoagulant and fibrinolytic action of protein C found in the plasma

Question 6

what is the Storage site of vwf in endothelium

a. alpha granules
b. dense granules
c. weibel palade

Answer 6

Von Willevbrand factor (vWF)

• Protein secreted by endothelium into subendothelium; required for platelet adhesion to site of vessel injury
• Storage site of vwf in endothelium- Weibel Palade
• Storage site of vwf in platelets: alpha granules

Question 7

controlled by vessel smooth muscle

a. vasoconstriction
b. platelet adhesion
c. platelet aggregation
d. fibrin platelet plug formation

Answer 7

vasoconstriction

• controlled by vessel smooth muscle
• enhanced by chemical secreted platelets

Question 8

platelets adhere to exposed to subendothelial connective tissues

a. vasoconstriction
b. platelet adhesion
c. platelet aggregation
d. fibrin platelet plug formation

Answer 8

platelet adhesion

• platelets adhere to EXPOSED to subendothelial connective tissues

Question 9

Coagulation factors interact on platelet surface to produce fibrin

a. vasoconstriction
b. platelet adhesion
c. platelet aggregation
d. fibrin platelet plug formation

Answer 9

fibrin platelet plug formation

• Coagulation factors interact on platelet surface to produce fibrin
  
  • fibrin platelet plug

Question 10

It is triggered by G proteins

a. eicosanoid
b. IP-DAG pathway

Answer 10

G proteins

• Controls the cellular activation for all cells at the inner membrane surface Eicosanoid Called as prostaglandin, cyclooxygenase, or thromboxane pathway
• It is triggered by G proteins

Inositol triphosphate Diacylglycerol (IP3-DAG pathway)
- Second G protein dependent activation