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HPIM 19th Hema > Hemolytic Anemias > Flashcards

Hemolytic Anemias Flashcards

1
Q

Infection in which the MC cause of Hemolytic anemia in non-malaria endemic areas

A

E.coli O157:H7

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2
Q

Features of Hemolytic Anemia

A 
Splenomegaly
Dec haptoglobin
Inc MCV and MCHC
Unconjugated hyperbilirubinemia
Reticulocytosis
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3
Q

Deficiency in Hereditary Spherocytosis

A

Spectrin and Ankyrin

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4
Q

Definitive treatment for hereditary spherocytosis

A

Splenectomy

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5
Q

Diagnostic of choice for Thalassemia syndromes

A

Hgb electrophoresis

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6
Q

Features of G6PD Deficiency

A

Hemighosts
Bite Cells
Heinz Bodies
Poikilocytes

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7
Q

Clinical triad of PNH

A

Hemolytic anemia + Venous thrombosis + Deficient hematopoesis

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8
Q

Diagnostic modality for PNH

A 
Flow Cytometry
(CD55 and CD59)
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9
Q

Definitive treatment of PNH

A

Hematopoietic stem cell transplant (HSCT)

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HPIM 19th Hema (7 decks)

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