hemoglobinopathies Flashcards
1
Q
HbS
A
Valine at 6th
2
Q
Hb C
A
Lysine at 6th
3
Q
Hb D
A
Glycine at 121
4
Q
Hb E
A
Lysine at 6th
5
Q
most common hemoglobin variant
A
Hb S
6
Q
has an apparent immunity to P falciparum
A
Hb S
7
Q
pathogenesis of sickle disease
A
02 decreases leading to polymerization of hemoglobin causing the formation of crystals
8
Q
sickling occurs at what percent
A
85%
9
Q
primary cause of death in sickle cell disease
A
infectious crises
10
Q
primary screening method for abnormal hemoglobin
A
alkaline hgb electrophoresis
11
Q
method of choice when screening newborn for abnormal hemoglobin
A
acid hgb electrophoresis
12
Q
hemoglobinopathy that produces methemoglobin
A
Hb M
13
Q
also known as congenital heinz body hemolytic anemia
A
unstable hemoglobin disease
