anemia of bone marrow and systemic disorders

Question 1

aplastic anemia

Answer 1

failure to produce all formed elements of blood

Question 2

how to diagnose aplastic anemia

Answer 2

2 out of 3
- hgb <100 g/L
- granulocyte count <1.5 x 10^9/L
- platelet count <50 x x 10^9/L

Question 3

laboratory findings of aplastic anemia

Answer 3

dry tap bone marrow
normocytic normochromic anemia

Question 4

fanconi anemia

Answer 4

congenital AA
-chromosome instability disorder

Question 5

pure red cell aplasia

Question 6

diamond blackfan anemia

Answer 6

congenital prca

Question 7

congenital prca

Answer 7

diamond blackfan anemia

Question 8

congenital dyserythropoietic anemia

Answer 8

refractory anemia caused by ineffective erythropoiesis

Question 9

BM aspirate of CDA`

Answer 9

normoblast with multinuclearity, karyorrhexis and bizzare malformation

Question 10

type 1 CDA

Answer 10

slightly macrocytic
CDAN1gene mutation

Question 11

type 2 CDA

Answer 11

normocytic
most common form
HEMPAS

Question 12

HEMPAS

Answer 12

type 2 CDA
hereditary erythroblast multinuclearity with positive acidified serum test
(-)OFT

Question 13

leukoeryhtroblastosis

Answer 13

myelophthisic anemia

Question 14

myelophthisic anemia

Answer 14

caused by malignant tumors destruction and replacement of hsc

Question 15

laboratory findings of myelophthisic anemia

Answer 15

dacrocyte shift to left

Question 16

abnormal cell found in myelophthisic anemia

Answer 16

dacrocyte

Question 17

abnormal cell found in anemia of chronic kidney disease

Answer 17

burr cell/ echinocyte

Question 18

decreased cortisol

Answer 18

addison’s disease

Question 19

anemia of pregnancy usually develops and increase around what week?

Answer 19

8th week and increases until 32-34th week