Hemoglobin Flashcards
1
Q
Hemoglobin
A
a multisubunit protein (displays quaternary protein structure) that uses a heme coenzyme group to bind and transport oxygen
2
Q
Quarternary subunits
A
2 alpha helices and 2 beta sheets
3
Q
Myoglobin vs Hemoglobin
A
Hemoglobin(higher binding affinity) pO2 is @ 26 torr while myoglobin pO2 is at 2.8 torr
Myoglobin has 1 binding site
Hemoglobin has 4 binding sites
4
Q
Positive Cooperativity
A
the binding of the first oxygen makes it easier for the second one and the second one makes it easier for the 3rd, but when the fourth one binds it makes it near impossible CALLED NEGATIVE COOPERITIVITY
5
Q
2,3-BPG
A
binds to hemoglobin and decreases its binding affinity for oxygen.
