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RECALLS : Biochem > Hemo Myo Nutri Vita > Flashcards

Hemo Myo Nutri Vita Flashcards

1
Q

Increase in 2,3 BPG
a. Lowers affinity for o2 increase p50
b. Lowers affinity for o2 decrease p50
c. Increases affinity for o2 increase p50
d. Increases affinity for o2 decrease p50

A

Lowers affinity for o2 increase p50

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2
Q

Which of the following is true of heme?
a. Planar network of unconjugated double bonds gives its deep red color
b. Ferrous iron is positioned in the center through bonds with the 4 nitrogens of the porphyrinogen ring
c. Linkage of alpha methyne bridges
d. Complex of porphyrinogen IX and iron

A

Linkage of alpha methyne bridges

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3
Q

Deficiency of vitamin K is common in individuals with
a. Cephalosporin medications
b. Gastrectomy
c. Chronic alcoholism
d. Isoniazid treatment

A

Cephalosporin medications

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4
Q

Symptom of Vitamin D toxicity
a. Hypertension
b. Dermatitis
c. Diarrhea
d. Weakness

A

Hypertension

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5
Q

Function of Hemoglobin
A. Transport 02 and c02
B. Carry O2 to the lungs

A

Transport 02 and c02

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6
Q

Nutrient X to Protein Y

A

Proteome activity

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7
Q

Formation of carboxyglutamate needs the participation of
A. Vitamin A
B. Vitamin D
C. Vitamin E
D. Vitamin K

A

Vitamin K

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8
Q

What vitamin deficiency is common in carcinoid syndrome?
A. Biotin
B. Carotene
C. Niacin
D. Pantothenic acid

A

Niacin

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9
Q

What causes folate trap
A. Folate deficiency
B. Vit. B12 deficiency
C. Excess folate precursors
D. Excess vit B12

A

Vitamin B12 deficiency

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10
Q

Which is not a symptom of scurvy?
A. Demineralization of bone
B. Gum decay
C. Fragile blood capillaries
D. Tooth loss

A

Demineralization of bone

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11
Q

Night blindness is characterized by
A. Increase sensitivity to dim light
B. Increase sensitivity to green light
C. May lead to loss of visual cells
D. Decrease lacrimation

A

May lead to loss of visual cells

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12
Q

Pure vegetarians are at risk of developing this Vitamin deficiency
A. Folic
B. Vitamin B12
C. Niacin
D. Pyridoxine

A

Vitamin B12

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13
Q

Direct effect of low levels of TPP in the brain
a. Increase lactate
b. Increase dopamine
c. Cell repair
d. Increase activity of alpha-ketoglutarate dehydrogenase

A

Increase lactate

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14
Q

Which has diabetes milletus
I. HbA1C 6.0
II. RBS 11.1
III. OGTT 11.1
IV. FBS 126 6 hours fasting

Choices are
A. I, II, III
B. II only
C. III only
D. II and III

A

III only

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15
Q

gene-diet-disease interaction?
A. 97% percent of the disease causing mutations are monogenic mutations
B. Monogenic mutations affect the kind of food an individual consumes and therefore responsible for the manifestations of certain diseases
C. An individual’s gene and diet interact very closely to determine their health status
D. All of the above

A

All of the above

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16
Q

Fava beans
a. Vitamin C
B. Vitamin D
C. Acetylcholine receptors
d. Cytosolic receptors

A

Vitamin D

17
Q

Hemoglobin M

A

His F8 replaced with tyrosine

18
Q

An infant patient born normally, but needs BT after 1yr 2 yr of life
a. A thalassemia trait
B. B thalassemia minor
C. Methemoglobinemia
D. B thalassemia major

A

B thalassemia major

19
Q

Deamination and condensation reactions are dependent on what vitamin
a. Pyridoxal phosphate
b. FMN
c. Vitamin B12
d. Vitamin B6

A

Vitamin B6

20
Q

Why does carbon monoxide not fully adhere to the heme in some cases?
a. Apoprotein of myoglobin and hemoglobin
B. Angle of heme
C. Hindered environment
D. All of the above

A

All of the above

21
Q

The role of ApoE4 in Alzheimer’s Disease:
a. Increase cholesterol synthesis
B. Hampers tangle formation
C. Increases mitochondrial function
D. Suppresses apoptosis

A

Increase cholesterol synthesis

22
Q

Retinol esters from the diet are hydrolyzed in the
a. Retina
B. Intestinal mucosa
C. Adipose tissue
D. Liver

A

Intestinal mucosa

23
Q

Patients with St John wort…. Should be cautioned with
a. Drug interaction
B. Depression
C. Hyperthyroidism
D. Hypertriglyceridemia

A

Drug interaction

24
Q

Example of dihydrofolate reductase inhibitor
a. Pyrazinamide
b. Vincristine
c. Trimethoprim
d. Ethambutol

A

Trimethoprim

25
Q

Iron is slightly out of place secondary to steric repulsion because proximal His and N atoms or porphyrin

A

Cooperative binding

26
Q

Vitamin D plant of origin
a. Ergocalciferol
b. Cholecalciferol
C. 7 dihydroxycholecalciferol
D. 7 deoxy calciferol

A

Ergocalciferol

27
Q

Which of the following is not a Vit B12 dependent enzymes
a. Methionine synthase
B. Alpha-ketoglutarate dehydrogenase
C. Methylmalonyl COA mutase
D. Leucine aminomutase

A

Alpha-ketoglutarate dehydrogenase

28
Q

Prevents non enzymatic oxidation of cell components like polyunsaturated fatty acids
a. Vitamin A
b. Vitamin D
c. Vitamin E
d. Vitamin K

A

Vitamin E

29
Q

Intake of avidin will lead to this vitamin deficiency
a. Thiamine deficiency
B. Biotin
C. Folic acid
D. Pantothenic acid

A

Biotin

30
Q

Deficiency of vitamin E in premature infants will lead to
a. Hemolytic anemia
B. Pernicious anemia
C. Megaloblastic anemia
D. Bleeding

A

Hemolytic anemia

31
Q

Pruritic skin and headache are few signs of
a. Pellagra
B. Hypervitaminosis A
C. Wernicke-Korsakoff syndrome

A

Hypervitaminosis A

32
Q

Effects of several nutrients (including macronutrients and micronutrients) on the genome and explores the interaction between genes and nutrients of food bioactives and their effects on human health

a. Nutrigenomics
b. Nutrigenetics

A

Nutrigenomics

33
Q

Which of the following best describes FTO gene?
a. The BMI-increasing allele is less prevalent in populations with European ancestry
b. FTO confers increased risk of obesity by increasing cholesterol level
c. FTO SNPs do not influence physical activity levels

A

FTO SNPs do not influence physical activity levels

34
Q

Lactic acidosis is common in patients with this vitamin deficiency
a. Thiamine
B. Niacin
c. Biotin
D.Riboflavin

A

Thiamine

RECALLS : Biochem (5 decks)

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