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Master The Boards > Heme > Flashcards

Heme Flashcards

1
Q

Initial test for anemia

A

CBC

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2
Q

Accurate test for iron deficiency anemia

A

BM biopsy for stainable Fe

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3
Q

Treatment for iron deficiency anemia

A

Oral Fe Sulfate > IM

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4
Q

Accurate test for sideroblastic anemia

A

Prussian blue for ringed sideroblasts

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5
Q

Accurate test for thalassemia

A

Hb electrophoresis

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6
Q

Accurate test for B12 deficiency

A

Ab testing (pernicious)

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7
Q

Treatment for b12 deficiency

A

1 B12 shot per month

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8
Q

Treatment for folate deficiency

A

Daily oral folate

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9
Q

Initial test for macrocytic anemia

A

Peripheral smear (visualize hypersegmented neutrophils)

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10
Q

Treatment for stroke due to SCD

A

Exchange transfusion

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11
Q

Initial test for SCD

A

Peripheral smear (Howell jolly bodies)

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12
Q

Accurate test for SCD

A

Hb electrophoresis

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13
Q

Treatment for Parvo B19 in SCD

A

IVIG

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14
Q

Accurate test for ParvoB19

A

PCR

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15
Q

Treatment for SCD that improves mortality

A

Hydroxyurea + Abx in fever

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16
Q

Accurate test for hereditary spherocytosis

A

Osmotic fragility test

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17
Q

Treatment for hereditary spherocytosis

A

Folic acid + splenectomy

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18
Q

Accurate test for AI hemolysis

A

Coombs (IgG)

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19
Q

Treatment for AI Hemolysis

A

Glucocorticoids > IVIG > Splenectomy > Rituximab

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20
Q

Accurate test for cold agglutins disease

A

Cold agglutins titer

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21
Q

Treatment for cold agglutins disease

A

Stay warm + Rituximab

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22
Q

Initial test for G6PDD

A

Smear to look for Heinz bodies + bite cells

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23
Q

Accurate test for G6PDD

A

G6PD level 1-2 months later

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24
Q

Treatment for HUS/TTP

A

plasmapheresis

25
Q

Accurate test for PNH

A

Flow cytometry (decreased CD55/59)

26
Q

Treatment for PNH

A

Prednisone > BMT > Eculizumab

27
Q

Accurate test for aplastic anemia

A

BM biopsy

28
Q

Treatment for aplastic anemia

A

Transfusion + Abx + platelets (acute)BMT (young)ATG + Cyclosporine (old)

29
Q

Accurate test for PV

A

JAK2 mutation

30
Q

Treatment for PV (4)

A

Phlebotomy/ASA + hydroxyurea + allopurinol + antiHis

31
Q

Treatment for ET (2)

A

Hydroxyurea + ASA

32
Q

Treatment for AML

A

ATRA

33
Q

Initial test for leukemia

A

Blood smear (shows blasts)

34
Q

Accurate test for leukemia

A

Flow cytometry

35
Q

Additional treatment for ALL vs AML

A

Intrathecal MTX

36
Q

Treatment for stage 3/4 CLL

A

Fludarabine + cyclophosphamide + Rituximab

37
Q

Accurate test for CML

A

FISH/PCR (for bclABL)

38
Q

Treatment for CML

A

Imatinib > BMT

39
Q

Treatment for leukostatsis rxn

A

Leukophoresis

40
Q

Treatment for 5q deletion causing myelodysplastic syndrome

A

Lenalidonide

41
Q

Initial test for hairy cell

A

Smear

42
Q

Accurate test for hairy cell

A

Flow cytometry

43
Q

Treatment for hairy cell

A

Cladribine or Pentostatin

44
Q

Initial test for NHL

A

Excisional biopsy

45
Q

Treatment for stage 3/4 NHL

A

Rituximab + CHOP (cyclophosphamide/Adramycin/Vincristine/Prednisone)

46
Q

Treatment for HL

A

ABVD (Adramycin/Bleomycin/Vinblastine/Dacarbazine)

47
Q

Initial test for MM (2)

A

SPEP (IgG or IgA) + X-ray showing lytic lesions

48
Q

Accurate test for MM

A

BM biopsy shows >10% plasma cells

49
Q

Treatment for Waldenstrom

A

Plasmapheresis

50
Q

Treatment for ITP

A

Steroids > IVIG > splenectomy > Romiplastin

51
Q

Treatment for vWD

A

DDAVP > Factor 8

52
Q

Accurate test for hemophilia

A

Specific assay for factors 8 and 9

53
Q

Treatment for hemophilia

A

DDAVP > Factor 8 + 9

54
Q

Treatment for DIC

A

FFP > Cryo

55
Q

Treatment for HIT

A

Stop Hep + direct inhibitor + Warfarin

56
Q

Accurate test for HIT (2)

A

ELISA (PF4 abs)Serotonin release assay

57
Q

Accurate test for APS

A

Russell viper venom

58
Q

Initial test for APS

A

PTT elevated which does not correct

59
Q

Treatment for APS

A

Hep/Warfarin forever

Master The Boards (4 decks)

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