Hematopoietic system Flashcards

1
Q

• is a connective tissue that consists of a liquid matrix containing cells and cell fragments.

A

Blood

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Liquid matrix occupies how many percent of total blood volume

A

55%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Formed elements makes up how many percent?

A

45%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Total blood volume in average adult female

A

is 4-5 liters

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Total blood volume in adult male

A

5-6 L

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

 the blood is what% of the total body weight.

A

8%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

is the pale yellow fluid portion of the blood.

A

Plasma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Percentage of water, proteins, and others like ions, nutrients…

A

91% water
7% proteins
2% others

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

• comprises majority of the plasma proteins in the blood

A

Albumin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

is part of the immune system. It has a role as transport molecules, so it transports other cells. And some are clotting factors like fibrinogen.

A

Globulins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

• is then converted to fibrin, which is a thread like protein that forms the blood clots.

A

Fibrinogen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

• majority of the proteins in the blood

A

Albumin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

• this is plasma without the presence of your clotting factors like your fibrinogen.

A

Serum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

3 fomed elements

A

RBC
WBC
Platelet

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

• are otherwise known as erythrocytes.
• They are the most abundant formed elements in the plot,

A

RBCs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

RBCs comprise how many percent?

A

95%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

WBC are known as

A

Leukocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Platelets are known as

A

Thrombocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

• Is the process that produces those formed elements.

A

Hematopoeisis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

In fetus, hematopoeisis occur in several tissues such as?

A

Liver
Thymus
Spleen
Lymph nodes
Red bone marrow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Stem cells is otherwise known as

A

Hemocytoblast

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

this is where all the formed elements are derived from. So this is the mother cell of the different formed elements.

A

Stem cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

3 different white blood cells

A

Basophil
Eosinophil
Neutrophil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

• is the protein responsible for the red color of your red blood cells. It makes up 1 third of the RBC volume.

A

Hemoglobin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

hemoglobin is broken down into how many globin and heme.

A
  1. Globin chain
    4 heme group
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

• red blood cells contain the?

A

Protein hemoglobin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

General function of RBC

A

• is to transport oxygen or pick up oxygen from the lungs to be distributed to the various tissues of the body. In exchange, it transports carbon dioxide that was used by your tissues to the lungs.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

is the actual red pigmented molecule.

A

Heme

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

 each contains or each heme group contains how many iron atom which can bind to an oxygen molecule.

A

1 iron atom

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

How many heme group in 1 RBC

A

4 heme group

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

How many oxygen molecule can hemoglobin carry?

A

4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

If it is bound to oxygen, it has a what color?

A

Bright red

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

If not bound to any oxygen, what’s the color?

A

Darker red

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

The production of your RBCs is stimulated by

A

Low blood oxygen levels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

• is stimulated by low blood oxygen, levels. This will release what hormone?

A

Erythropoietin

36
Q

Releasing erythropoietin in where?

A

Kidneys

37
Q

What happens when the RBCs have become old or has reached its lifespan or is abnormal or damaged?

A

• it will go to the spleen and in the spleen, it is degraded through the process of phagocytosis by the macrophages.

38
Q

What happens to the globin in spleen?

A

it is degraded or broken down into its simplest form which is the amino acid. So this amino acid is being reused by the body.

39
Q

What happens to heme

A

Heme is converted into bilirubin which is a yellow pigment.

40
Q

• is essential in breaking down or emulsifying fat from the food that we eat.

A

Bile

41
Q

the brownish or yellowish pigment of your stool.

A

Stercobilin

42
Q

the yellow pigment that is found in your urine.

A

Urobilin

43
Q

what happens to hemoglobin When the RBCs are broken down?

A

• the hemoglobin is also broken down. The globin part of the hemoglobin is protein, so therefore, it is broken down into its simplest form, which is amino acids. And then this amino acid is being recycled or reutilized by the body.

44
Q

• these are spherical shaped cells larger than RBCs.

A

WBCs

45
Q

Are WBC nucleated or annucleated

A

Nucleated

46
Q

• the movement of the WBCs is called

A

Amoeboid

47
Q

• Still under deformed elements, these are fragments of cells as they are derived from megakaryocytes. So, please remember that they are just fragments of cells

A

Platelets

48
Q

Platelets are nucleate or annucleate?

A

Annucleate

49
Q

Major function of platelets

A

Hemostasis

50
Q

• is the process to prevent and stop bleeding. So these are the mechanisms of the body that would stop the bleeding.

A

Hemostasis

51
Q

Stasis means?

Hemo means?

A

Stop

Blood

52
Q

the 3 processes involved in hemostasis are the following.

A
  1. Vascular spasm
  2. Platelete plug formation
  3. Blood clotting itself
53
Q

• So the goal of the vascular spasm

A

Contract or constrict

54
Q

This will release ______ in the kidneys to stimulate the bone marrows to produce red blood cells.

A

Erythropoietin

55
Q

• the movement of the WBCs is called ?

A

Ameboid movement

56
Q

It is to protect the body against pathogen and remove dead cells and debris from the tissues by phagocytosis.

A

WBCS

57
Q

Both of these will induce vasospasm. Or vascular spasm.

A

Thromboxane from platelet
Endothelin from endothelial cells

58
Q

• is the accumulation of platelets that can seal up a small break in the blood vessel.

A

Platelet plug

59
Q

endothelial cells will also release this very important factor,

A

Von willebrand factor

60
Q

endothelial cells will also release this very important factor,

A

Von willebrand factor

61
Q

importance of your von Willebrand factor. So, with the collagen exposed, plus the presence of your von Willebrand factor, your platelets will be able to adhere. This is the process called

A

Platelet adhesion

62
Q

they form a bridge between the exposed collagen and the platelets.

A

Von willebrand factor

63
Q

they form a bridge between the exposed collagen and the platelets.

A

Von willebrand factor

64
Q

The platelets on that site will release chemicals such as your

A

ADP
THROMBOXANE

65
Q

Once there’s already receptors for fibrinogen on the platelets, the platelets will bind to fibrinogen. This is the process

A

Platelet aggregation

66
Q

Stages of blood clotting

A

Activation of blood clotting factor
Conversion of prothrombin to thrombin
Conversion of fibrinogen to fibrin

67
Q

Stages of blood clotting

A

Activation of blood clotting factor
Conversion of prothrombin to thrombin
Conversion of fibrinogen to fibrin

68
Q

• Prothrombin(inactive) converts to thrombin (active form) through the

A

Prothrombinase enzyme

69
Q

blood clotting is the conversion of fibrinogen into fibrin through the help of your

A

Thrombin

70
Q

o This is the organ that creates or synthesizes your clotting factors.

A

Liver

71
Q

cutting factors require what vitamin for synthesis.

A

Vitamin k

72
Q

Vitamin K can be synthesized not only taken from the food that we eat but also from the?

A

Bacteria

73
Q

chemicals that are found in the blood are your?

A

Heparin
Antithrombin

74
Q

Anticoagulants in the blood

A

o antithrombin
o heparin

75
Q

Abnormal clots

A

Thrombus
Embolus

76
Q

o are clots that are attached at the damaged or diseased areas of the blood vessel.

A

Thrombus

77
Q

o this is when the thrombus breaks loose and begins to flow through the circulation

A

Embolus

78
Q

two processes to complete the process of hemostasis.

A

Clot retractions
Fibrinolysis

79
Q

these 2 are present, it signifies that the platelet is able to contract.

A

Actin and myosin filaments

80
Q

So the main actor in the process of fibrinolysis is your

A

Plasminogen

81
Q

So the main actor in the process of fibrinolysis is your

A

Plasminogen

82
Q

inactive plasma protein, so it has to be converted to its active form

A

Plasminogen

83
Q

This is released from the surrounding tissues, and then this can stimulate the conversion of plasminogen to plasmin

A

Tissue plasminogen activator TPA

84
Q

is a medication that is actually, injected, IV, to the patients who are sus suspected with, blood clots. So they will help dissolve the clots by converting plasminogen to plasmin, and then the plasmin itself will break down the fibrin

A

Streptokinase

85
Q

is a medication that is actually, injected, IV, to the patients who are sus suspected with, blood clots. So they will help dissolve the clots by converting plasminogen to plasmin, and then the plasmin itself will break down the fibrin

A

Streptokinase