hematopoietic a&p Flashcards
blood components
plasma formed elements - wbc - rbcs - platelets
3 parts of the plasma
clotting factors
albumin
immunoglobulins
blood components job
transportation, regulating temp, fluid balance, ph
plasma (in-depth)
55%
- largest component of blood
- yellowish tinge
- transporting medium
- regulates body temp, ph
- becomes warm as it goes thru organs than distributes heat
plasma transporting medium
- composed of 91% water
- contains clotting factors, albumin, globulins
albumin
blood plasma protein. pulls fluid
globulins
immunoglobins
leukocytes
wbcs
- main component of immunity
- normal count: 5,000-10,000
- subdivided into 5 types
neutrophils
help fight bacteria infection
eosinophils
allergic reactions type 1
basophils
bone marrow disorder/inflammation
lymphocytes
viral infection/chronic infection
- t cells
- b cells
monocytes
- chronic infection
erythrocytes
rbc
- most populace
- disk-shaped
- contain hemoglobin
- 120 days
erthrocytes lab values
rbcs: 4-6 million
- hemoglobin Male: 14-17 gm/dl
Female: 12-15 gm/dl
- hemtocrit
-M: 40-50%
- F: 36-44%
thrombocytes
platelets
- formed in bone marrow
- responsible for hemostasis
- controls coagulation
- vascular spasm
- platelet plug
- normal count: 150,000- 450,000
hematopoiesis
utero and adult
- blood formation
in utero
- initially in rbcs only - remainder of blood components
adulthood
- primarily controlled by bone marrow - spleen aids in production - maturation
maturation
cell maturing
- thymus
- bone marrow
- peripheral blood
- tissue
hemostasis
- process in which bleeding stops
- multi-stage process
hemostasis multi-stage process stages
vasoconstriction
- vessels narrow, decreasing flow to the site of injury
- results in increased bp
platelet plug formation
- activation: chemicals released
- aggregation: plaletes sticking together
- adherence: adhere to the wall- temporarily platlet plug
coagulation
- referred to as clotting cascade
- fibrinogen –> fibrin—> blood clot
fibrinogen
mesh network, stable clot
changes with age: decrease volume
less blood volume so there is less of a reservoir in the event of blood loss
changes with age: decrease bone marrow activity
becomes infiltrated with things like fat and fibrotic tissues
changes with age: antibody response
lead to things like a slower response to foreign antigens
changes with age: rate of cell production
leads to anemia
changes with age: increase platelet aggregation
blood is more prone to coagulate
lymphatic system
- main connection to spleen
- located in RUQ
- filters blood, removed pathogens and old blood cells and helps in the producing of lymphocytes
- serves as a reservoir for extra blood
- if removed body accommodates and the spleen and liver take over the function
during hemorrhage the spleen:
spleen contracts forced some of the stored blood out of the spleen and into the cardiovascular system
physical assessment signs: vital signs
- increase hr
- increase RR
physical assessment signs: LOC
irritability
confusion
physical assessment signs: skin color
pallor
cyanosis
jaundice
physical assessment signs: signs of bleeding
ecchymosis
petechiae
physical assessment signs: fingernails
striations
spoon-shaped
clubbing
physical assessment signs: abdomen
- increase girth
- changes in BS
- black/tarry stools and coffee ground emesis
physical assessment signs: activity intolerance
- increase oxygen demand
vasoconstriction
- vessels narrow, decreasing flow to the site of injury
- results in increased bp
platelet plug
- activation: chemicals released
- aggregation: plates sticking together
- adherence: adhere to the wall- temporarily platelet plug
coagulation
- referred to as clotting cascade
- fibrinogen –> fibrin—> blood clot