Hematology Flashcards
What is the most abundant protein in the blood plasma?
albumin
25% of protein in the blood consists of what?
IgG
What study is used to measure plasma proteins?
protein electrophoresis
What measurement is used to assays liver function test?
albumin
How much albumin is produced by the liver per day and this represents what % of total hepatic protein synthesis?
- 12g albumin per day
- 25% of total hepatic protein synthesis
What is the half-life of albumin?
20 days
Hypoalbuminemia can be seen in what 3 diseased states?
- malnutrition
- nephrotic syndrome
- cirrhosis of liver
Albuminuria can be seen in what 2 diseased states?
- nephrotic syndrome
- UTI
Albumin can be therapeutically used for the treatment of what?
burns and hemorrhage
What is 1 example of an alpha-1 globulin?
a. a1-antitrypsin
What are 3 examples of alpha-2 globulins?
- Haptoglobin
- Ceruloplasmin
- Angiotensinogen
Which alpha 2 globulin is an acute phase reactant responsible for binding with free hemoglobin in the blood to prevent renal failure?
Haptoglobin
*alpha 2 globulin
If this protein is low in the blood this is an indicator of hemolysis.
b. haptoglobin
* alpha 2 globulin
What is the copper carrying protein in the blood?
c. cerulopasmin
* alpha 2 globulin
What is the protein that when activated turns into plasma and works to dissolve fibrin clot?
d. plasminogen
* Beta-globulin
