Hematology Flashcards

1
Q

Sickle Cell disease

- preferred diagnostic test

A
  • high performance liquid chromatography
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2
Q

Sickle cell disease

- lab findings

A
  • normochromic anemia
  • elevated LDH
  • decreased haptoglobin
  • increased indirect bilirubin
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3
Q

ITP

- common patient/pt history

A
  • child 2-6 yo

- recent viral infection

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4
Q

ITP

- clinical

A
  • petechiae
  • purpura
  • gingival bleeding
  • platelets <100k
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5
Q

ITP

- mgmt

A
  • observation
  • steroids
  • IVIG
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6
Q

INR goal for pt on warfarin for mechanical mitral valve replacement

A

2.5-3.5

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7
Q

G6PD deficiency

- drugs to avoid

A
  • antimalarials
  • sulfas
  • nitrofurantoin
  • fava beans
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8
Q

G6PD deficiency

- labs

A
  • heinz bodies

- bite cells on smear

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9
Q

Which clotting factors are K dependent

A

2, 7, 9, 10

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10
Q

Heparin reversal agent

A

Protamine sulfate

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11
Q

Warfarin reversal agent

A

Vitamin K

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12
Q

Heparin induced thrombocytopenia

A
  • recently started heparin
  • 50% decrease in platelets
  • stop heparin, start direct thrombin inhibitor
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13
Q

Where is folate absorbed

A

jejunum

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14
Q

where is B12 absorbed

A

ileum

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15
Q

where is iron absorbed

A

duodenum

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16
Q

B12 and folate deficiency

- elevations of homocysteine and methymalonic acid

A

B12: both
folate: just homocysteine