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PANCE > Derm > Flashcards

Derm Flashcards

1
Q

Pemphigus Vulgaris

  • common age
  • patho
  • RF
A
  • 40-60
  • autoantibodies target desmosomes
  • genetics, UV radiation, viral infection, drugs
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2
Q

Pemphigus Vulgaris

- clinical

A
  • mucosal involvement

- flaccid blisters + Nikolsky sign

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3
Q

Pemphigus Vulgaris

- dx

A

bx Histology: intraepithelial cleavage with pacantholysis, “chicken wire”

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4
Q

Pemphigus Vulgaris

- mgmt

A

high dose prednisone

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5
Q

Bullous Pemphigoid

- age

A

elderly MC

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6
Q

Bullous Pemphigoid

- clinical

A
  • large tense blisters

- negative nikolsky

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7
Q

Oral candidiasis

- infant mgmt

A
  • nystatin suspension

- pacifiers and bottle nipples boiled before reuse

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8
Q

Breast candidiasis

  • presentation
  • mgmt
A
  • sore nipples, deep, sharp shooting or burning pain
  • topic miconazole or clotrimazole
  • keep breastfeeding
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9
Q

Tinea Versicolor

  • presentation
  • bug
A
  • hypo- or hyper pigmented macules/patches ton chest and back
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10
Q

Tinea Versicolor

  • presentation
  • bug
A
  • hypo- or hyper pigmented macules/patches on chest and back
  • no itch to light itch
  • malassezia
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11
Q

Tinea versicolor

- mgmt

A
  • topical: selenium sulfide, zinc, ketoconazole

- neck to knees daily for 2 weeks

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12
Q

Cellulitis

- MC bug

A
  • GAS

- also s. aureus

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13
Q

What is group A strep also known as

A

strep pyogenes

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14
Q

Cellulitis

- mgmt

A

mild: PO cephalexin
Purulent: Clinda, Bactrim, Doxy
Severe: parenteral - cefazolin or vanc

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15
Q

Melanoma

  • 4 types
  • which is MC
A
  1. Superficial spreading (MC)
  2. nodular
  3. Lentigo
  4. Acral lentiginous
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16
Q

Melanoma

- what is used to determine prob of metastasis?

A

Breslow depth scale

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17
Q

Melanoma

- ABCDE

A 
A: asymmetry
B: irregular border
C: variegated color
D: diameter ≥ 6 mm
E: Evolution, change
18
Q

Melanoma

- ABCDE

A 
A: asymmetry
B: irregular border
C: variegated color
D: diameter ≥ 6 mm
E: Evolution, change
19
Q

Melanoma

- dx

A

histology of complete full-thickness excisions bx

20
Q

Melanoma

- mgmt

A

Surgical excision with adequate margin (1 cm)

21
Q

Erythema Multiforme

- MC etiology

A

Herpes simplex virus

- usu herpes labialis

22
Q

Erythema Multiforme

- overview

A
  • immune-mediated disorder > cutaneous and sometimes mucosal lesions
  • hypersensitivity reaction
23
Q

Erythema Multiforme

- major vs minor

A
  • Major: cutaneous and mucosal, has a prodrome

- Minor: just cutaneous involvement

24
Q

Erythema Multiforme

- clinical

A
  • target-like lesions
  • red papule with surrounding pallor and outside red halo
  • few to hundreds
  • appear over 3-4 days, last 2-6 weeks
  • usu asx, but can burn or itch
25
Q

Erythema Multiforme

- mgmt

A

steroids
- mild: topical
- severe: systemic
+ antihistamine for itching

eliminate offending agent, acyclovir if HSV

26
Q

Erythema Nodosum

  • patho
  • triggers
A
  • immune-mediated delayed hypersensitivity reaction

- infection, drugs, inflammatory dz

27
Q

Erythema Nodosum

- clinical

A
  • tender, immobile, red nodular lesions

- bilateral anterior LE

28
Q

Erythema Nodosum

- mgmt

A
  • elevation, compression of legs

- NSAIDs

29
Q

Chickenpox

- vaccination

A

12-15 months

4-6 years

30
Q

Chickenpox

- when is antiviral therapy recommended

A
  • Pt >12 yo
  • at risk pts
  • all adults
    • acyclovir
31
Q

Stasis Dermatitis

- cause

A

chronic venous insufficiency

32
Q

Stasis Dermatitis

- skin changes

A
  • hyper pigmentation
  • eczema
  • fibrosis
33
Q

Stasis Dermatitis

- RF

A
  • older age
  • F
  • obesity
  • standing frequently
34
Q

Stasis Dermatitis

- mgmt

A
  • compression
  • emollients/lotions to moisturize
  • topical steroids, wet dressings
  • abx if cellulitis
35
Q

Lichen Simplex Chronicus

- overview

A
  • chronically pruritic skin

- related to constant scratching or rubbing of area = fibrosis

36
Q

Lichen Simplex Chronicus

- clinical

A
  • excoriated and lichenified skin

- itch scratch cycle

37
Q

Lichen Simplex Chronicus

- RF

A
  • depression/anxiety
  • liver dz
  • atopic dermatitis
38
Q

Lichen Simplex Chronicus

- mgmt

A
  • ID and curb compulsion to scratch

- steroids, antihistamines, antidepressants

39
Q

Pediculosis capitus

- mgmt

A
  • topical permethrin (MC), malathion, ivermectin
  • treat household members who share th same bedding or are infested also
  • Wash clothing/linen used 48 hours before treatment in hot water
40
Q

Psoriasis

- patho

A
  • up regulation of dendritic cells
41
Q

Vitiligo

- patho

A

autoimmune melanocyte destruction

PANCE (14 decks)

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