Hematology Flashcards
Blood:
Blood is a unique organ because it is a ______.
Fluid
Blood:
Composed of plasma, various cells, proteins, ______ _____, electrolytes, nutrients, to include ___, and waste products.
Clotting factors;O2
Blood:
Formed by bone marrow in response to ____ ___ level.
low O2
Hematopoiesis:
Occurs in 5 days.
____ O2 level-> stimulates kidney to secrete _______, which increases erythroblast formation, which forms ___________ (immature RBCs)
Low; erythropoitin; reticulocytes
Hematopoiesis:
If rapid erythropoiesis is necessary may release ________ and nucleated _____. After maturity, cells live about ____ days
reticulocytes; RBCs; 120
RBC Function:
95% of cell mass is ________.
Have no nucleus.
Flexible and disk shaped to facilitate ________ and release of gases.
hemoglobin; absorption;
RBC function:
Transport gases through _______. Main function-transport of O2 between ______. Also aids in buffer system
diffusion; lungs
RBC needs:
_____ stores and metabolism.
Vitamin ____ and folic acid metabolism. Destruction.
Iron; B12
WBC:
Total amount = 5,000- 10,000
-60-70% are ________
-30-40% are _________
granulocytes; lymphocytes
WBC function:
Protect against bacterial invasion and other foreign entities. Name the 5 components of WBCs and their function.
- Neutrophils- Fast arrival for short lived phagocytosis
- monocytes- long term phagocytosis
- lymphocytes- produces substances that attack foreign material that kill directly or that enhance phagocytic cells (T). B cells differentiate into plasma cells which produce immunoglobulins
- Eosinophils- allergic reactions (neutralizes histamine) and phagocytosis of parasites
- basophils produce and store histamine which when released provokes an allergic reaction.
Other Components:
Platelets (thrombocytes)- granular Fragments.
Where are they produced?
In the marrow
Other components:
What are platelets regulated by?
the hormone thrombopoitin
Other components:
Platelets control bleeding, how exactly do they do this?
Collect and activate at the site of injury forming a plug. They release substances that activate coagulation factors.
Other components:
Platelets also nurture and maintaining the ______ of the vessels.
lining
Other components: Plasma and plasma proteins 90%=water rest=plasma proteins, \_\_\_\_\_\_ \_\_\_\_\_, nutrient enzymes, waste and \_\_\_\_\_\_\_. -serum -proteins- albumin, globulins
clotting factors; gases
