Hematology

Question 1

Smudge Cells

Answer 1

CLL

Question 2

Tetrads or Maltese Cross Inclusions in RBCs

Answer 2

Babesia

Question 3

Giant Platelets

Answer 3

Bernard-Soulier Disease, ITP, Agnogenic Myeloid Metaplasia

Question 4

Bite Cell, Blister Cell

Answer 4

G6PD deficiency

Question 5

Burr Cell (Echinocyte)

Answer 5

Uremia

Question 6

Spurr Cell (Acanthocyte)

Answer 6

Anemia of Liver Disease

Question 7

Morulae, Inclusions in Cytoplasm

Answer 7

Human Ehrlichiosis (Anaplasmosis)

Question 8

Platelets >800,000

Answer 8

Thrombocytosis (Essential?). Check JAK2.

Question 9

Spherocytes with Increased MCV, Reticulocytes

Answer 9

Hereditary Spherocytosis, AIHA

Question 10

Hairy Cells, TRAP stain positive, Pancytopenia

Answer 10

Hairy Cell Leukemia

Question 11

Howell-Jolly Bodies

Answer 11

Post-Splenectomy, Functional Asplenia

Question 12

Isolated Thrombocytopenia with normal HB, PT/PTT, occasional megakaryocyte

Answer 12

ITP

Question 13

Atypical Lymphocytes

Answer 13

Mononucleosis

Question 14

Microcytic, Hypochromic RBCs

Answer 14

Iron Deficiency Anemia

Question 15

Basophillic Stippling

Answer 15

Lead Poisoning

Question 16

Ring Forms in RBC

Answer 16

Malaria

Question 17

Hypersegmented Neutrophils, MCV >115, Hypercellular BM

Answer 17

Megaloblastic Anemia 2/2 B12/Folate Deficiency

Question 18

Hyposegmented (Pelger-Huet) Neutrophils, MCV

Answer 18

Myelodysplastic Syndrome

Question 19

Plasma Cells in smear

Answer 19

Multiple Myeloma

Question 20

Tear-drop cells

Answer 20

MMMF

Question 21

Roleaux Formation of RBCs

Answer 21

MM, MGUS

Question 22

Agglutinated RBCs

Answer 22

Mycoplasma Infection, Blood Incompatibility

Question 23

High RBCs, Low/Normal Epo, Prurtitis after Bathing

Answer 23

Polycythemia Vera

Question 24

Target Cells

Answer 24

Sickle Cell Anemia, Thalassemia, HbC, HbE, EtOH abuse

Question 25

Reed-Sternberg Cell

Answer 25

Hodgkin’s Lymphoma

Question 26

Schistocytes

Answer 26

HUS/TTP, DIC, HELLP, Prosthetic Valve